A numeric model consisting of a lump-parameter cardiovascular system (CVS) model and a model for the Cleveland Clinic Implantable ventricular Assist System (IVAS) were developed. IVAS is a pulsatile rotary pump designed to augment the failing left ventricle. The hemodynamic interactions between CVS and IVAS under various physiologic and pathophysiologic conditions running at different speeds and the various IVAS control algorithms were investigated. The numeric modeling proved to be useful in predicting hemodynamic response of CVS to IVAS in various circumstances. Computer simulations also showed that IVAS resulted in normalization of cardiac output, especially in failing hearts at reduced pulse pressure.
ASJC Scopus subject areas
- Biomedical Engineering