Obesity and the insulin resistance syndrome

Lewis Landsberg*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

24 Scopus citations


Obesity is one component of a risk factor constellation that consists of insulin resistance (and/or hyperinsulinemia), hypertension, and a dyslipidemia characterized by a low HDL cholesterol level and high triglyceride levels. This risk factor constellation, which conveys enhanced risk for cardiovascular disease, is sometimes referred to as the "insulin resistance syndrome", "syndrome x", or the "metabolic" syndrome. Although the hyperinsulinemia and insulin resistance associated with the syndrome appear to play a central role, the relationship between insulin and the other manifestations of the syndrome have remained obscure.

Original languageEnglish (US)
Pages (from-to)S51-S55
JournalHypertension Research
Issue numberSUPPL. 1
StatePublished - Jun 1996


  • Insulin resistance
  • Obesity
  • Sympathetic nervous system

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology
  • Cardiology and Cardiovascular Medicine


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