Obesity in pregnancy: Data from the hyperglycemia and adverse pregnancy outcome (HAPO) study

Harold David McIntyre*, Lynn P. Lowe, Alan R. Dyer, Boyd E. Metzger

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Scopus citations


The Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study has provided an opportunity to assess the relative associations of maternal glycemia measured at an oral glucose tolerance test (mean 28 weeks gestation) and maternal body mass index with a range of adverse pregnancy outcomes, without many of the potential confounding factors seen in previous studies. The HAPO study confirmed independently significant associations between maternal BMI and birthweight >90th centile, frequency of primary cesarean section, neonatal hypoglycemia, neonatal hyperinsulinemia, preeclampsia, and neonatal adiposity. The combination of maternal obesity and gestational diabetes was associated with higher frequencies of adverse outcomes than either variable in isolation.

Original languageEnglish (US)
Title of host publicationMaternal Obesity and Pregnancy
PublisherSpringer-Verlag Berlin Heidelberg
Number of pages11
ISBN (Electronic)9783642250231
ISBN (Print)364225022X, 9783642250224
StatePublished - Oct 1 2012

ASJC Scopus subject areas

  • General Medicine


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