Renal biopsies obtained from four adolescent girls who developed symptomatic thrombocytopenia with serologicevidence of systemiclupus erythematosus, without clinical signs of renal involvement, showed glomerular disease by electron and immunofluorescent microscopy with light microscopic changes in two cases. Subsequently, three of the patients developed proteinuria, and repeat biopsies from all four showed appearances ranging from resolution to significant glomerulitis. The findings illustrate the variable patterns of occult glomerulitis in Iupus, and highlight the value of correlating light, electron and immunofluorescent studies in renal pathology.
|Original language||English (US)|
|Number of pages||19|
|State||Published - Nov 1977|
- glomerular deposits
- lupus nephropathy
ASJC Scopus subject areas
- Pathology and Forensic Medicine