Occult pneumococcal bacteremia: A review

Mark D. Joffe, Elizabeth R. Alpern

Research output: Contribution to journalReview articlepeer-review

29 Scopus citations

Abstract

Occult bacteremia is primarily caused by Streptococcus pneumoniae and has been an intense clinical controversy in pediatric emergency medicine, with passionate opinions rendered from inside and outside the field. Vaccine development and widespread immunization have rapidly affected the changing epidemiology of this disease. There is a growing consensus that the reduction in incidence of occult bacteremia and the significant problem of antibiotic resistance are tipping the balance in favor of no testing and no treatment for well-appearing febrile children between 6 and 36 months of age who are immunized with Haemophilus influenzae B vaccination and PCV-7 (pneumococcal conjugate vaccine). This review of occult pneumococcal bacteremia will not only elaborate on current knowledge and clinical practice, but will also provide historical context to this fascinating phenomenon.

Original languageEnglish (US)
Pages (from-to)448-457
Number of pages10
JournalPediatric emergency care
Volume26
Issue number6
DOIs
StatePublished - Jun 1 2010

Keywords

  • Bacteremia
  • Streptococcus pneumoniae

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Emergency Medicine

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