Occupational allergic alveolitis

Leslie C. Grammer

doi:10.1016/s1081-1206(10)62880-3

Occupational allergic alveolitis

Leslie C. Grammer^*

^*Corresponding author for this work

Medicine, Allergy Division

Research output: Contribution to journal › Review article › peer-review

21 Scopus citations

Abstract

Hypersensitivity pneumonitis is an important occupational pulmonary disease. A variety of antigens including foreign proteins and low molecular weight chemicals have been described as etiologic agents. The immunopathogenesis appears to involve activated CD8+ cells as well as activated macrophages. The clinical disease may be acute, subacute or chronic depending upon the nature and level of exposure. Reducing exposure to known antigens is a strategy that appears promising in terms of prevention of irreversible disease.

Original language	English (US)
Pages (from-to)	602-606
Number of pages	5
Journal	Annals of Allergy, Asthma and Immunology
Volume	83
Issue number	6 II
DOIs	https://doi.org/10.1016/s1081-1206(10)62880-3
State	Published - Dec 1999

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Pulmonary and Respiratory Medicine

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10.1016/s1081-1206(10)62880-3

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title = "Occupational allergic alveolitis",

abstract = "Hypersensitivity pneumonitis is an important occupational pulmonary disease. A variety of antigens including foreign proteins and low molecular weight chemicals have been described as etiologic agents. The immunopathogenesis appears to involve activated CD8+ cells as well as activated macrophages. The clinical disease may be acute, subacute or chronic depending upon the nature and level of exposure. Reducing exposure to known antigens is a strategy that appears promising in terms of prevention of irreversible disease.",

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AU - Grammer, Leslie C.

PY - 1999/12

Y1 - 1999/12

N2 - Hypersensitivity pneumonitis is an important occupational pulmonary disease. A variety of antigens including foreign proteins and low molecular weight chemicals have been described as etiologic agents. The immunopathogenesis appears to involve activated CD8+ cells as well as activated macrophages. The clinical disease may be acute, subacute or chronic depending upon the nature and level of exposure. Reducing exposure to known antigens is a strategy that appears promising in terms of prevention of irreversible disease.

AB - Hypersensitivity pneumonitis is an important occupational pulmonary disease. A variety of antigens including foreign proteins and low molecular weight chemicals have been described as etiologic agents. The immunopathogenesis appears to involve activated CD8+ cells as well as activated macrophages. The clinical disease may be acute, subacute or chronic depending upon the nature and level of exposure. Reducing exposure to known antigens is a strategy that appears promising in terms of prevention of irreversible disease.

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U2 - 10.1016/s1081-1206(10)62880-3

DO - 10.1016/s1081-1206(10)62880-3

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AN - SCOPUS:0033402793

SN - 1081-1206

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JO - Annals of Allergy, Asthma and Immunology

JF - Annals of Allergy, Asthma and Immunology

IS - 6 II

ER -

Occupational allergic alveolitis

Abstract

ASJC Scopus subject areas

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