OCT angiography and visible-light OCT in diabetic retinopathy

Peter L. Nesper; Brian T. Soetikno; Hao F. Zhang; Amani A. Fawzi

doi:10.1016/j.visres.2017.05.006

OCT angiography and visible-light OCT in diabetic retinopathy

Peter L. Nesper, Brian T. Soetikno, Hao F. Zhang, Amani A. Fawzi^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

48 Scopus citations

Abstract

In recent years, advances in optical coherence tomography (OCT) techniques have increased our understanding of diabetic retinopathy, an important microvascular complication of diabetes. OCT angiography is a non-invasive method that visualizes the retinal vasculature by detecting motion contrast from flowing blood. Visible-light OCT shows promise as a novel technique for quantifying retinal hypoxia by measuring the retinal oxygen delivery and metabolic rates. In this article, we discuss recent insights provided by these techniques into the vascular pathophysiology of diabetic retinopathy. The next milestones for these modalities are large multicenter studies to establish consensus on the most reliable and consistent outcome parameters to study diabetic retinopathy.

Original language	English (US)
Pages (from-to)	191-203
Number of pages	13
Journal	Vision Research
Volume	139
DOIs	https://doi.org/10.1016/j.visres.2017.05.006
State	Published - Oct 2017

Keywords

Diabetic retinopathy
Imaging
OCT
OCT angiography
Retina
Visible-light OCT

ASJC Scopus subject areas

Ophthalmology
Sensory Systems

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.visres.2017.05.006

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title = "OCT angiography and visible-light OCT in diabetic retinopathy",

abstract = "In recent years, advances in optical coherence tomography (OCT) techniques have increased our understanding of diabetic retinopathy, an important microvascular complication of diabetes. OCT angiography is a non-invasive method that visualizes the retinal vasculature by detecting motion contrast from flowing blood. Visible-light OCT shows promise as a novel technique for quantifying retinal hypoxia by measuring the retinal oxygen delivery and metabolic rates. In this article, we discuss recent insights provided by these techniques into the vascular pathophysiology of diabetic retinopathy. The next milestones for these modalities are large multicenter studies to establish consensus on the most reliable and consistent outcome parameters to study diabetic retinopathy.",

keywords = "Diabetic retinopathy, Imaging, OCT, OCT angiography, Retina, Visible-light OCT",

author = "Nesper, {Peter L.} and Soetikno, {Brian T.} and Zhang, {Hao F.} and Fawzi, {Amani A.}",

note = "Publisher Copyright: {\textcopyright} 2017 Elsevier Ltd",

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doi = "10.1016/j.visres.2017.05.006",

language = "English (US)",

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T1 - OCT angiography and visible-light OCT in diabetic retinopathy

AU - Nesper, Peter L.

AU - Soetikno, Brian T.

AU - Zhang, Hao F.

AU - Fawzi, Amani A.

PY - 2017/10

Y1 - 2017/10

N2 - In recent years, advances in optical coherence tomography (OCT) techniques have increased our understanding of diabetic retinopathy, an important microvascular complication of diabetes. OCT angiography is a non-invasive method that visualizes the retinal vasculature by detecting motion contrast from flowing blood. Visible-light OCT shows promise as a novel technique for quantifying retinal hypoxia by measuring the retinal oxygen delivery and metabolic rates. In this article, we discuss recent insights provided by these techniques into the vascular pathophysiology of diabetic retinopathy. The next milestones for these modalities are large multicenter studies to establish consensus on the most reliable and consistent outcome parameters to study diabetic retinopathy.

AB - In recent years, advances in optical coherence tomography (OCT) techniques have increased our understanding of diabetic retinopathy, an important microvascular complication of diabetes. OCT angiography is a non-invasive method that visualizes the retinal vasculature by detecting motion contrast from flowing blood. Visible-light OCT shows promise as a novel technique for quantifying retinal hypoxia by measuring the retinal oxygen delivery and metabolic rates. In this article, we discuss recent insights provided by these techniques into the vascular pathophysiology of diabetic retinopathy. The next milestones for these modalities are large multicenter studies to establish consensus on the most reliable and consistent outcome parameters to study diabetic retinopathy.

KW - Diabetic retinopathy

KW - Imaging

KW - OCT

KW - OCT angiography

KW - Retina

KW - Visible-light OCT

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OCT angiography and visible-light OCT in diabetic retinopathy

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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