OCT angiography and visible-light OCT in diabetic retinopathy

Peter L. Nesper, Brian T. Soetikno, Hao F. Zhang, Amani A. Fawzi*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

48 Scopus citations


In recent years, advances in optical coherence tomography (OCT) techniques have increased our understanding of diabetic retinopathy, an important microvascular complication of diabetes. OCT angiography is a non-invasive method that visualizes the retinal vasculature by detecting motion contrast from flowing blood. Visible-light OCT shows promise as a novel technique for quantifying retinal hypoxia by measuring the retinal oxygen delivery and metabolic rates. In this article, we discuss recent insights provided by these techniques into the vascular pathophysiology of diabetic retinopathy. The next milestones for these modalities are large multicenter studies to establish consensus on the most reliable and consistent outcome parameters to study diabetic retinopathy.

Original languageEnglish (US)
Pages (from-to)191-203
Number of pages13
JournalVision Research
StatePublished - Oct 2017


  • Diabetic retinopathy
  • Imaging
  • OCT
  • OCT angiography
  • Retina
  • Visible-light OCT

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems


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