Ocular biomechanics and biotransport

C. Ross Ethier*, Mark Johnson, Jeff Ruberti

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

220 Scopus citations


The eye transduces light, and we usually do not think of it as a biomechanical structure. Yet it is actually a pressurized, thick-walled shell that has an internal and external musculature, a remarkably complex internal vascular system, dedicated fluid production and drainage tissues, and a variety of specialized fluid and solute transport systems. Biomechanics is particularly involved in accommodation (focusing near and far), as well as in common disorders such as glaucoma, macular degeneration, myopia, and presbyopia. In this review, we give a (necessarily brief) overview of many of the interesting biomechanical aspects of the eye, concluding with a list of open problems.

Original languageEnglish (US)
Pages (from-to)249-273
Number of pages25
JournalAnnual Review of Biomedical Engineering
StatePublished - 2004


  • Aqueous humor drainage
  • Bruch's membrane
  • Cornea
  • Glaucoma
  • Optic nerve head

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Biomedical Engineering


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