Oculocutaneous Albinism, Platelet Storage Pool Disease, and Progressive Lupus Nephritis

John S. Bomalaski, David Green*, Frank Carone

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

Systemic lupus erythematosus (SLE) was seen in a patient with oculocutaneous albinism and platelet storage pool disease (Hermansky Pudlak syndrome). Although the patient had severely compromised platelet function, lupus nephritis developed nonetheless, which progressed to end-stage renal disease. The role of platelets in the pathogenesis of the nephritic process is discussed, and it is concluded that release of platelet granular constituents, particularly serotonin, is not required for the microvascular damage of SLE.

Original languageEnglish (US)
Pages (from-to)809-811
Number of pages3
JournalArchives of Internal Medicine
Volume143
Issue number4
DOIs
StatePublished - Apr 1983

ASJC Scopus subject areas

  • Internal Medicine

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