Office-Based Procedures for the Diagnosis and Treatment of Laryngeal Pathology

David J. Wellenstein*, Henrieke W. Schutte, Robert P. Takes, Jimmie Honings, Henri A.M. Marres, James A. Burns, Guido B. van den Broek

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

40 Scopus citations


Introduction: Since the development of distal chip endoscopes with a working channel, diagnostic and therapeutic possibilities in the outpatient clinic in the management of laryngeal pathology have increased. Which of these office-based procedures are currently available, and their clinical indications and possible advantages, remains unclear. Material and Methods: Review of literature on office-based procedures in laryngology and head and neck oncology. Results: Flexible endoscopic biopsy (FEB), vocal cord injection, and laser surgery are well-established office-based procedures that can be performed under topical anesthesia. These procedures demonstrate good patient tolerability and multiple advantages. Conclusion: Office-based procedures under topical anesthesia are currently an established method in the management of laryngeal pathology. These procedures offer medical and economic advantages compared with operating room-performed procedures. Furthermore, office-based procedures enhance the speed and timing of the diagnostic and therapeutic process.

Original languageEnglish (US)
Pages (from-to)502-513
Number of pages12
JournalJournal of Voice
Issue number4
StatePublished - Jul 2018


  • Biopsy
  • Laser surgery
  • Local anesthesia
  • Office-based procedure
  • Vocal cord injection

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Speech and Hearing
  • LPN and LVN


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