Older adult oncology, version 1.2021: Featured updates to the NCCN guidelines

Efrat Dotan; Louise C. Walter; Ilene S. Browner; Katherine Clifton; Harvey Jay Cohen; Martine Extermann; Cary Gross; Sumati Gupta; Genevieve Hollis; Joleen Hubbard; Reshma Jagsi; Nancy L. Keating; Elizabeth Kessler; Thuy Koll; Beatriz Korc-Grodzicki; June M. McKoy; Sumi Misra; Dominic Moon; Tracey O’Connor; Cynthia Owusu; Ashley Rosko; Marcia Russell; Mina Sedrak; Fareeha Siddiqui; Amy Stella; Derek L. Stirewalt; Ishwaria M. Subbiah; William P. Tew; Grant R. Williams; Liz Hollinger; Giby V. George; Hema Sundar

doi:10.6004/jnccn.2021.0043

Older adult oncology, version 1.2021: Featured updates to the NCCN guidelines

Efrat Dotan, Louise C. Walter, Ilene S. Browner, Katherine Clifton, Harvey Jay Cohen, Martine Extermann, Cary Gross, Sumati Gupta, Genevieve Hollis, Joleen Hubbard, Reshma Jagsi, Nancy L. Keating, Elizabeth Kessler, Thuy Koll, Beatriz Korc-Grodzicki, June M. McKoy, Sumi Misra, Dominic Moon, Tracey O’Connor, Cynthia OwusuAshley Rosko, Marcia Russell, Mina Sedrak, Fareeha Siddiqui, Amy Stella, Derek L. Stirewalt, Ishwaria M. Subbiah, William P. Tew, Grant R. Williams, Liz Hollinger, Giby V. George, Hema Sundar

Medicine, Geriatrics Division

Research output: Contribution to journal › Review article › peer-review

91 Scopus citations

Abstract

The NCCN Guidelines for Older Adult Oncology address specific issues related to the management of cancer in older adults, including screening and comprehensive geriatric assessment (CGA), assessing the risks and benefits of treatment, preventing or decreasing complications from therapy, and managing patients deemed to be at high risk for treatment-related toxicity. CGA is a multidisciplinary, in-depth evaluation that assesses the objective health of the older adult while evaluating multiple domains, which may affect cancer prognosis and treatment choices. These NCCN Guidelines Insights focus on recent updates to the NCCN Guidelines providing specific practical framework for the use of CGA when evaluating older adults with cancer.

Original language	English (US)
Pages (from-to)	1006-1019
Number of pages	14
Journal	JNCCN Journal of the National Comprehensive Cancer Network
Volume	19
Issue number	9
DOIs	https://doi.org/10.6004/jnccn.2021.0043
State	Published - Sep 2021

Funding

This activity is supported by educational grants from Agios Pharmaceuticals; AstraZeneca; Clovis Oncology, Inc.; Daiichi Sankyo; Eisai; Epizyme Inc.; Novartis; and Pharmacyclics LLC, an AbbVie Company and Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC. This activity is supported by an independent medical education grant from Bristol-Myers Squibb, and Regeneron Pharmaceuticals, Inc. and Sanofi Genzyme. This activity is supported by an independent medical educational grant from Mylan Inc. This activity is supported by a medical education grant from Karyopharm Therapeutics. This activity is supported by an independent educational grant from AbbVie. Efrat Dotan, MD, Panel Chair, has disclosed receiving grant/research support from AstraZeneca Pharmaceuticals LP, Boston Biomedical, Eli Lilly and Company, Incyte Corporation, Ipsen, MedImmune Inc., and Pfizer Inc. Louise C. Walter, MD, Panel Vice Chair, has disclosed no relevant financial relationships. Liz Hollinger, BSN, RN, Guidelines Layout Specialist, NCCN, has disclosed no relevant financial relationships. Giby V. George, MD, Oncology Scientist/Medical Writer, NCCN, has disclosed no relevant financial relationships. Hema Sundar, PhD, Manager, Global Clinical Content, NCCN, has disclosed no relevant financial relationships.

ASJC Scopus subject areas

Oncology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.6004/jnccn.2021.0043

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Dotan, E., Walter, L. C., Browner, I. S., Clifton, K., Cohen, H. J., Extermann, M., Gross, C., Gupta, S., Hollis, G., Hubbard, J., Jagsi, R., Keating, N. L., Kessler, E., Koll, T., Korc-Grodzicki, B., McKoy, J. M., Misra, S., Moon, D., O’Connor, T., ... Sundar, H. (2021). Older adult oncology, version 1.2021: Featured updates to the NCCN guidelines. JNCCN Journal of the National Comprehensive Cancer Network, 19(9), 1006-1019. https://doi.org/10.6004/jnccn.2021.0043

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abstract = "The NCCN Guidelines for Older Adult Oncology address specific issues related to the management of cancer in older adults, including screening and comprehensive geriatric assessment (CGA), assessing the risks and benefits of treatment, preventing or decreasing complications from therapy, and managing patients deemed to be at high risk for treatment-related toxicity. CGA is a multidisciplinary, in-depth evaluation that assesses the objective health of the older adult while evaluating multiple domains, which may affect cancer prognosis and treatment choices. These NCCN Guidelines Insights focus on recent updates to the NCCN Guidelines providing specific practical framework for the use of CGA when evaluating older adults with cancer.",

author = "Efrat Dotan and Walter, {Louise C.} and Browner, {Ilene S.} and Katherine Clifton and Cohen, {Harvey Jay} and Martine Extermann and Cary Gross and Sumati Gupta and Genevieve Hollis and Joleen Hubbard and Reshma Jagsi and Keating, {Nancy L.} and Elizabeth Kessler and Thuy Koll and Beatriz Korc-Grodzicki and McKoy, {June M.} and Sumi Misra and Dominic Moon and Tracey O{\textquoteright}Connor and Cynthia Owusu and Ashley Rosko and Marcia Russell and Mina Sedrak and Fareeha Siddiqui and Amy Stella and Stirewalt, {Derek L.} and Subbiah, {Ishwaria M.} and Tew, {William P.} and Williams, {Grant R.} and Liz Hollinger and George, {Giby V.} and Hema Sundar",

year = "2021",

month = sep,

doi = "10.6004/jnccn.2021.0043",

language = "English (US)",

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Dotan, E, Walter, LC, Browner, IS, Clifton, K, Cohen, HJ, Extermann, M, Gross, C, Gupta, S, Hollis, G, Hubbard, J, Jagsi, R, Keating, NL, Kessler, E, Koll, T, Korc-Grodzicki, B, McKoy, JM, Misra, S, Moon, D, O’Connor, T, Owusu, C, Rosko, A, Russell, M, Sedrak, M, Siddiqui, F, Stella, A, Stirewalt, DL, Subbiah, IM, Tew, WP, Williams, GR, Hollinger, L, George, GV & Sundar, H 2021, 'Older adult oncology, version 1.2021: Featured updates to the NCCN guidelines', JNCCN Journal of the National Comprehensive Cancer Network, vol. 19, no. 9, pp. 1006-1019. https://doi.org/10.6004/jnccn.2021.0043

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AU - Cohen, Harvey Jay

AU - Extermann, Martine

AU - Gross, Cary

AU - Gupta, Sumati

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AU - McKoy, June M.

AU - Misra, Sumi

AU - Moon, Dominic

AU - O’Connor, Tracey

AU - Owusu, Cynthia

AU - Rosko, Ashley

AU - Russell, Marcia

AU - Sedrak, Mina

AU - Siddiqui, Fareeha

AU - Stella, Amy

AU - Stirewalt, Derek L.

AU - Subbiah, Ishwaria M.

AU - Tew, William P.

AU - Williams, Grant R.

AU - Hollinger, Liz

AU - George, Giby V.

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Older adult oncology, version 1.2021: Featured updates to the NCCN guidelines

Abstract

Funding

ASJC Scopus subject areas

UN SDGs

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