Oligonucleotide Flexibility Dictates Crystal Quality in DNA-Programmable Nanoparticle Superlattices

Andrew J. Senesi, Daniel J. Eichelsdoerfer, Keith A. Brown, Byeongdu Lee, Evelyn Auyeung, Chung Hang J. Choi, Robert J. MacFarlane, Kaylie L. Young, Chad A. Mirkin*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

38 Scopus citations


The evolution of crystallite size and microstrain in DNA-mediated nanoparticle superlattices is dictated by annealing temperature and the flexibility of the interparticle bonds. This work addresses a major challenge in synthesizing optical metamaterials based upon noble metal nanoparticles by enabling the crystallization of large nanoparticles (100 nm diameter) at high volume fractions (34% metal).

Original languageEnglish (US)
Pages (from-to)7235-7240
Number of pages6
JournalAdvanced Materials
Issue number42
StatePublished - Nov 1 2014


  • DNA
  • X-ray scattering
  • ligand flexibility
  • metamaterials
  • superlattices

ASJC Scopus subject areas

  • Mechanics of Materials
  • Mechanical Engineering
  • Materials Science(all)


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