On the need for improved transfusion indicators in cardiac surgery

Lawrence T. Goodnough*, George J. Despotis, Charles W. Hogue, T. Bruce Ferguson

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

87 Scopus citations


Guidelines for transfusion practice have had limited impact in altering physician transfusion behavior in patients undergoing cardiac operations. This may be due to a lack of consensus on the relative risks and benefits of blood in these patients who are anemic, limited access to timely data that are necessary on which to base transfusion decisions, the recognition that empiric hemoglobin/hematocrit thresholds are limited clinical indicators of the need for blood, or a combination of these. We present an overview of current transfusion and blood conservation practices in this setting, along with possible approaches to guide the decision-making process by coupling the use of transfusion algorithms with point of care testing to use more physiologic indicators of the need for blood transfusion.

Original languageEnglish (US)
Pages (from-to)473-480
Number of pages8
JournalThe Annals of thoracic surgery
Issue number2
StatePublished - Aug 1995

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Pulmonary and Respiratory Medicine
  • Surgery


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