One-year outcomes of a randomized clinical trial treating depression in low-income minority women

Jeanne Miranda*, Juned Siddique, Tom Belin, Bonnie L. Green, Janice L. Krupnick, Joyce Chung, Dennis Revicki

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

79 Scopus citations


This study examines 1-year depressive symptom and functional outcomes of 267 predominantly low-income, young minority women randomly assigned to antidepressant medication, group or individual cognitive-behavioral therapy (CBT), or community referral. Seventy-six percent assigned to medications received 9 or more weeks of guideline-concordant doses of medications; 36% assigned to psychotherapy received 6 or more CBT sessions. Intent-to-treat, repeated measures analyses revealed that medication (p < .001) and CBT (p = .02) were superior to community referral in lowering depressive symptoms across 1-year follow-up. At Month 12, 50.9% assigned to antidepressants, 56.9% assigned to CBT, and 37.1% assigned to community referral were no longer clinically depressed. These findings suggest that both antidepressant medications and CBT result in clinically significant decreases in depression for low-income minority women.

Original languageEnglish (US)
Pages (from-to)99-111
Number of pages13
JournalJournal of Consulting and Clinical Psychology
Issue number1
StatePublished - Feb 2006


  • Clinical trials
  • Cognitive-behavioral therapy
  • Depression
  • Ethnic-minority women

ASJC Scopus subject areas

  • Clinical Psychology
  • Psychiatry and Mental health

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