Oocyte maturation during folliculogenesis

Teresa K. Woodruff; Hoi C. Lee; Jaewang Lee; Maxwell Edmonds

doi:10.1016/B978-0-12-801238-3.64711-6

Oocyte maturation during folliculogenesis

Teresa K. Woodruff, Hoi C. Lee, Jaewang Lee, Maxwell Edmonds

Obstetrics and Gynecology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

The follicle is the basic unit of female reproductive biology. It is composed of a single oocyte, surrounded by its companion somatic cells (granulosa cells and theca cells). The bi-directional communication between oocytes and neighboring somatic cells is responsible for both oocyte and somatic cell growth and maturation. Every month, one dominant human follicle produces one meiotically and developmentally competent oocyte, through the “ovulation” process. Following ovulation, the oocyte is arrested in metaphase II stage (MII) of meiosis until fertilization with a male gamete which is called the sperm.

Original language	English (US)
Title of host publication	Encyclopedia of Reproduction
Publisher	Elsevier
Pages	172-175
Number of pages	4
ISBN (Electronic)	9780128151457
DOIs	https://doi.org/10.1016/B978-0-12-801238-3.64711-6
State	Published - Jan 1 2018

Keywords

Folliculogenesis
Granulosa cell
Growth
Maturation
Meiotic division
Oocyte
Oogenesis
Ovarian follicle
Somatic cell
Theca cell

ASJC Scopus subject areas

Medicine(all)

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10.1016/B978-0-12-801238-3.64711-6

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title = "Oocyte maturation during folliculogenesis",

abstract = "The follicle is the basic unit of female reproductive biology. It is composed of a single oocyte, surrounded by its companion somatic cells (granulosa cells and theca cells). The bi-directional communication between oocytes and neighboring somatic cells is responsible for both oocyte and somatic cell growth and maturation. Every month, one dominant human follicle produces one meiotically and developmentally competent oocyte, through the “ovulation” process. Following ovulation, the oocyte is arrested in metaphase II stage (MII) of meiosis until fertilization with a male gamete which is called the sperm.",

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AU - Lee, Jaewang

AU - Edmonds, Maxwell

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AB - The follicle is the basic unit of female reproductive biology. It is composed of a single oocyte, surrounded by its companion somatic cells (granulosa cells and theca cells). The bi-directional communication between oocytes and neighboring somatic cells is responsible for both oocyte and somatic cell growth and maturation. Every month, one dominant human follicle produces one meiotically and developmentally competent oocyte, through the “ovulation” process. Following ovulation, the oocyte is arrested in metaphase II stage (MII) of meiosis until fertilization with a male gamete which is called the sperm.

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KW - Growth

KW - Maturation

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KW - Oogenesis

KW - Ovarian follicle

KW - Somatic cell

KW - Theca cell

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Oocyte maturation during folliculogenesis

Abstract

Keywords

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