Oocyte maturation during folliculogenesis

Teresa K. Woodruff, Hoi C. Lee, Jaewang Lee, Maxwell Edmonds

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


The follicle is the basic unit of female reproductive biology. It is composed of a single oocyte, surrounded by its companion somatic cells (granulosa cells and theca cells). The bi-directional communication between oocytes and neighboring somatic cells is responsible for both oocyte and somatic cell growth and maturation. Every month, one dominant human follicle produces one meiotically and developmentally competent oocyte, through the “ovulation” process. Following ovulation, the oocyte is arrested in metaphase II stage (MII) of meiosis until fertilization with a male gamete which is called the sperm.

Original languageEnglish (US)
Title of host publicationEncyclopedia of Reproduction
Number of pages4
ISBN (Electronic)9780128151457
StatePublished - Jan 1 2018


  • Folliculogenesis
  • Granulosa cell
  • Growth
  • Maturation
  • Meiotic division
  • Oocyte
  • Oogenesis
  • Ovarian follicle
  • Somatic cell
  • Theca cell

ASJC Scopus subject areas

  • Medicine(all)


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