Oophorectomy versus salpingo-oophorectomy in Turner syndrome patients with Y-chromosome material: Clinical experience and current practice patterns assessment

Roopa Kanakatti Shankar*, Thomas H. Inge, Iris Gutmark-Little, Philippe F. Backeljauw

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Background/purpose Gonadectomy is recommended in Turner syndrome (TS) patients with Y-chromosome material due to high risk of tumor in the dysgenetic gonads. No recommendations exist on whether concurrent salpingectomy should be performed.

Methods A retrospective chart review of surgical procedure and histopathology in TS patients with Y-chromosome enrolled in a TS database was undertaken at Cincinnati Children's Hospital Medical Center. An electronic survey was sent to members of the International Pediatric Endosurgery Group to assess prevalent practice patterns and attitudes on gonadectomy and concurrent salpingectomy in this population.

Results In March 2011, 12/158 (8%) TS girls (mean age 6.6 years) enrolled in the database had TS with Y-chromosome. Gonadoblastoma was identified in 4/12 (33%) patients and 2/4 had malignant transformation to dysgerminoma and teratoma. Approach to gonadectomy was varied and 3/12 had concurrent salpingectomy. Fifty-four laparoscopic surgeons responded to the survey with no clear consensus on whether salpingectomy should be concurrently performed.

Conclusions TS patients with Y-chromosome have an increased risk of gonadal tumor development and gonadectomy is recommended. While there is no consensus among pediatric laparoscopic surgeons on concurrent salpingectomy, it is reasonable to consider this combination procedure.

Original languageEnglish (US)
Pages (from-to)1585-1588
Number of pages4
JournalJournal of pediatric surgery
Volume49
Issue number11
DOIs
StatePublished - Nov 1 2014
Externally publishedYes

Keywords

  • Gonadoblastoma
  • Laparoscopic gonadectomy
  • Salpingectomy
  • Turner syndrome
  • Y-chromosome

ASJC Scopus subject areas

  • Surgery
  • Pediatrics, Perinatology, and Child Health

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