TY - JOUR
T1 - Open source software for electric field Monte Carlo simulation of coherent backscattering in biological media containing birefringence
AU - Radosevich, Andrew J.
AU - Rogers, Jeremy D.
AU - Çapolu, Ilker R.
AU - Mutyal, Nikhil N.
AU - Pradhan, Prabhakar
AU - Backman, Vadim
N1 - Funding Information:
This study was supported by National Institute of Health Grant Nos. RO1CA128641 and R01EB003682. A.J. Radosevich is supported by a National Science Foundation Graduate Research Fellowship under Grant No. DGE-0824162.
PY - 2012/11
Y1 - 2012/11
N2 - We present an open source electric field tracking Monte Carlo program to model backscattering in biological media containing birefringence, with computation of the coherent backscattering phenomenon as an example. These simulations enable the modeling of tissue scattering as a statistically homogeneous continuous random media under the Whittle-Matérn model, which includes the Henyey-Greenstein phase function as a special case, or as a composition of discrete spherical scatterers under Mie theory. The calculation of the amplitude scattering matrix for the above two cases as well as the implementation of birefringence using the Jones N-matrix formalism is presented. For ease of operator use and data processing, our simulation incorporates a graphical user interface written in MATLAB to interact with the underlying C code. Additionally, an increase in computational speed is achieved through implementation of message passing interface and the semi-analytical approach. Finally, we provide demonstrations of the results of our simulation for purely scattering media and scattering media containing linear birefringence.
AB - We present an open source electric field tracking Monte Carlo program to model backscattering in biological media containing birefringence, with computation of the coherent backscattering phenomenon as an example. These simulations enable the modeling of tissue scattering as a statistically homogeneous continuous random media under the Whittle-Matérn model, which includes the Henyey-Greenstein phase function as a special case, or as a composition of discrete spherical scatterers under Mie theory. The calculation of the amplitude scattering matrix for the above two cases as well as the implementation of birefringence using the Jones N-matrix formalism is presented. For ease of operator use and data processing, our simulation incorporates a graphical user interface written in MATLAB to interact with the underlying C code. Additionally, an increase in computational speed is achieved through implementation of message passing interface and the semi-analytical approach. Finally, we provide demonstrations of the results of our simulation for purely scattering media and scattering media containing linear birefringence.
KW - Monte Carlo modeling
KW - birefringence
KW - coherent backscattering
UR - http://www.scopus.com/inward/record.url?scp=84870609985&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84870609985&partnerID=8YFLogxK
U2 - 10.1117/1.JBO.17.11.115001
DO - 10.1117/1.JBO.17.11.115001
M3 - Article
C2 - 23123973
AN - SCOPUS:84870609985
SN - 1083-3668
VL - 17
JO - Journal of Biomedical Optics
JF - Journal of Biomedical Optics
IS - 11
M1 - 115001
ER -