Operations for Atrial Fibrillation

A. John Camm, James Lewis Cox*, John P. Boineau, Richard B. Schuessler, T. Bruce Ferguson, Michael E. Cain, Bruce D. Lindsay, Peter B. Corr, Kathy M. Kater, Demetrios G. Lappas

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


Atrial fibrillation is the most common of all sustained cardiac arrhythmias, yet it has no effective medical or surgical therapy. During the past decade, multipoint computerized electrophysiological mapping systems were used to map both experimental and human atrial fibrillation. On the basis of these studies, a new surgical procedure was developed for atrial fibrillation. Between September 25, 1987, and May 1, 1991, this procedure was applied in 22 patients with either paroxysmal atrial flutter (n = 2). paroxysmal atrial fibrillation (n= 11), or chronic atrial fibrillation (n = 9) of 2 to 21 years' duration. All patients were refractory to all antiarrhythmic medications and each patient failed an average of 5.2 drugs preoperatively. There were no operative deaths and all perioperative morbidity resolved. All 22 patients have been cured of atrial fibrillation with surgery alone. One late isolated episode of atrial flutter occurred in a patient who is now receiving encainide. Preservation of atrial transport function has been documented in all of the patients postoperatively and all have experienced marked clinical improvement.

Original languageEnglish (US)
Pages (from-to)827-835
Number of pages9
JournalClinical Cardiology
Issue number10
StatePublished - Oct 1991


  • arrhythmia surgery
  • atrial fibrillation
  • atrial flutter
  • cerebral thromboembolism
  • electrophysiology
  • stroke
  • supraventricular arrhythmias

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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