TY - JOUR
T1 - Optical cross-sectional imaging of the macula with the retinal thickness analyzer in X-linked retinoschisis
AU - Tanna, Angelo P.
AU - Asrani, Sanjay
AU - Zeimer, Ran
AU - Zou, Shazhou
AU - Goldberg, Morton F.
N1 - Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.
PY - 1998/8
Y1 - 1998/8
N2 - Objective: To assess the morphologic characteristics of the foveal abnormality in juvenile X-linked retinoschisis using the scanning retinal thickness analyzer (RTA). This characteristic foveal abnormality is present in 83% to 100% of patients with X-linked retinoschisis and has not been demonstrated histopathologically. Methods: The RTA is a noncontact imaging device. The RTA scans an obliquely oriented slit laser beam across the macula to obtain a series of optical cross sections, which are digitized. Participants: The RTA was used to examine 7 eyes of 5 patients with X-linked retinoschisis. Results: The RTA demonstrated foveal schisis in all eyes examined. In 2 eyes of 2 patients, a single schisis cavity, with an inner leaf in a dome-shaped configuration, was present. In 4 eyes of 3 patients, a single schisis cavity containing fine strands was present. Some of these strands partially, and others completely, bridged the cavity. In 1 eye of 1 patient, 2 separate schisis cavities with bridging strands were present in the fovea. Conclusions: Scanning RTA is a noninvasive imaging modality capable of producing optical cross sections that demonstrate the extent and structural details of the foveal schisis in X-linked retinoschisis. Scanning RTA seems to be effective in the detection, characterization, and quantification of foveal schisis.
AB - Objective: To assess the morphologic characteristics of the foveal abnormality in juvenile X-linked retinoschisis using the scanning retinal thickness analyzer (RTA). This characteristic foveal abnormality is present in 83% to 100% of patients with X-linked retinoschisis and has not been demonstrated histopathologically. Methods: The RTA is a noncontact imaging device. The RTA scans an obliquely oriented slit laser beam across the macula to obtain a series of optical cross sections, which are digitized. Participants: The RTA was used to examine 7 eyes of 5 patients with X-linked retinoschisis. Results: The RTA demonstrated foveal schisis in all eyes examined. In 2 eyes of 2 patients, a single schisis cavity, with an inner leaf in a dome-shaped configuration, was present. In 4 eyes of 3 patients, a single schisis cavity containing fine strands was present. Some of these strands partially, and others completely, bridged the cavity. In 1 eye of 1 patient, 2 separate schisis cavities with bridging strands were present in the fovea. Conclusions: Scanning RTA is a noninvasive imaging modality capable of producing optical cross sections that demonstrate the extent and structural details of the foveal schisis in X-linked retinoschisis. Scanning RTA seems to be effective in the detection, characterization, and quantification of foveal schisis.
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U2 - 10.1001/archopht.116.8.1036
DO - 10.1001/archopht.116.8.1036
M3 - Article
C2 - 9715684
AN - SCOPUS:0032454587
SN - 0003-9950
VL - 116
SP - 1036
EP - 1041
JO - Archives of ophthalmology
JF - Archives of ophthalmology
IS - 8
ER -