Optical-resolution confocal photoacoustic microscopy

Konstantin Maslov; Hao F. Zhang; Song Hu; Lihong V. Wang

doi:10.1117/12.763889

Optical-resolution confocal photoacoustic microscopy

Konstantin Maslov^*, Hao F. Zhang, Song Hu, Lihong V. Wang

^*Corresponding author for this work

Biomedical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

15 Scopus citations

Abstract

A confocal photoacoustic microscope with improved lateral resolution has been developed by employing strongly-focused bright field optical illumination and spherically focused 75-MHz ultrasonic detection. The lateral resolution was experimentally measured to be 5 μm and the axial resolution was estimated to be 15 μm. The maximum imaging depth was demonstrated to be greater than 0.7 mm. In in vivo experiments, microvessels with a diameter of μ 5 μm are imaged in small animals.

Original language	English (US)
Title of host publication	Photons Plus Ultrasound
Subtitle of host publication	Imaging and Sensing 2008: The Ninth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics
DOIs	https://doi.org/10.1117/12.763889
State	Published - 2008
Event	9th Conference on Photons Plus Ultrasound: Imaging and Sensing 2008 - San Jose, CA, United States Duration: Jan 20 2008 → Jan 23 2008

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	6856
ISSN (Print)	1605-7422

Other

Other	9th Conference on Photons Plus Ultrasound: Imaging and Sensing 2008
Country/Territory	United States
City	San Jose, CA
Period	1/20/08 → 1/23/08

Keywords

Confocal microscopy
Photoacoustic tomography

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Atomic and Molecular Physics, and Optics
Radiology Nuclear Medicine and imaging
Biomaterials

Access to Document

10.1117/12.763889

Cite this

Maslov, K., Zhang, H. F., Hu, S., & Wang, L. V. (2008). Optical-resolution confocal photoacoustic microscopy. In Photons Plus Ultrasound: Imaging and Sensing 2008: The Ninth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics Article 68561I (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 6856). https://doi.org/10.1117/12.763889

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title = "Optical-resolution confocal photoacoustic microscopy",

abstract = "A confocal photoacoustic microscope with improved lateral resolution has been developed by employing strongly-focused bright field optical illumination and spherically focused 75-MHz ultrasonic detection. The lateral resolution was experimentally measured to be 5 μm and the axial resolution was estimated to be 15 μm. The maximum imaging depth was demonstrated to be greater than 0.7 mm. In in vivo experiments, microvessels with a diameter of μ 5 μm are imaged in small animals.",

keywords = "Confocal microscopy, Photoacoustic tomography",

author = "Konstantin Maslov and Zhang, {Hao F.} and Song Hu and Wang, {Lihong V.}",

year = "2008",

doi = "10.1117/12.763889",

language = "English (US)",

isbn = "9780819470317",

series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

booktitle = "Photons Plus Ultrasound",

note = "9th Conference on Photons Plus Ultrasound: Imaging and Sensing 2008 ; Conference date: 20-01-2008 Through 23-01-2008",

}

Maslov, K, Zhang, HF, Hu, S & Wang, LV 2008, Optical-resolution confocal photoacoustic microscopy. in Photons Plus Ultrasound: Imaging and Sensing 2008: The Ninth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics., 68561I, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 6856, 9th Conference on Photons Plus Ultrasound: Imaging and Sensing 2008, San Jose, CA, United States, 1/20/08. https://doi.org/10.1117/12.763889

Optical-resolution confocal photoacoustic microscopy. / Maslov, Konstantin; Zhang, Hao F.; Hu, Song et al.
Photons Plus Ultrasound: Imaging and Sensing 2008: The Ninth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics. 2008. 68561I (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 6856).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - Optical-resolution confocal photoacoustic microscopy

AU - Maslov, Konstantin

AU - Zhang, Hao F.

AU - Hu, Song

AU - Wang, Lihong V.

PY - 2008

Y1 - 2008

N2 - A confocal photoacoustic microscope with improved lateral resolution has been developed by employing strongly-focused bright field optical illumination and spherically focused 75-MHz ultrasonic detection. The lateral resolution was experimentally measured to be 5 μm and the axial resolution was estimated to be 15 μm. The maximum imaging depth was demonstrated to be greater than 0.7 mm. In in vivo experiments, microvessels with a diameter of μ 5 μm are imaged in small animals.

AB - A confocal photoacoustic microscope with improved lateral resolution has been developed by employing strongly-focused bright field optical illumination and spherically focused 75-MHz ultrasonic detection. The lateral resolution was experimentally measured to be 5 μm and the axial resolution was estimated to be 15 μm. The maximum imaging depth was demonstrated to be greater than 0.7 mm. In in vivo experiments, microvessels with a diameter of μ 5 μm are imaged in small animals.

KW - Confocal microscopy

KW - Photoacoustic tomography

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DO - 10.1117/12.763889

M3 - Conference contribution

AN - SCOPUS:42149106853

SN - 9780819470317

T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

BT - Photons Plus Ultrasound

T2 - 9th Conference on Photons Plus Ultrasound: Imaging and Sensing 2008

Y2 - 20 January 2008 through 23 January 2008

ER -

Optical-resolution confocal photoacoustic microscopy

Abstract

Publication series

Other

Keywords

ASJC Scopus subject areas

Access to Document

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