Optical-resolution confocal photoacoustic microscopy

Konstantin Maslov*, Hao F. Zhang, Song Hu, Lihong V. Wang

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

11 Scopus citations


A confocal photoacoustic microscope with improved lateral resolution has been developed by employing strongly-focused bright field optical illumination and spherically focused 75-MHz ultrasonic detection. The lateral resolution was experimentally measured to be 5 μm and the axial resolution was estimated to be 15 μm. The maximum imaging depth was demonstrated to be greater than 0.7 mm. In in vivo experiments, microvessels with a diameter of μ 5 μm are imaged in small animals.

Original languageEnglish (US)
Title of host publicationPhotons Plus Ultrasound
Subtitle of host publicationImaging and Sensing 2008: The Ninth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics
StatePublished - 2008
Event9th Conference on Photons Plus Ultrasound: Imaging and Sensing 2008 - San Jose, CA, United States
Duration: Jan 20 2008Jan 23 2008

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


Other9th Conference on Photons Plus Ultrasound: Imaging and Sensing 2008
Country/TerritoryUnited States
CitySan Jose, CA


  • Confocal microscopy
  • Photoacoustic tomography

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging


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