Optimization of a planar all-polymer transistor for characterization of barrier tissue

Marc Ramuz*, Kaleigh Margita, Adel Hama, Pierre Leleux, Jonathan Rivnay, Ingrid Bazin, Rõisín M. Owens

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

The organic electrochemical transistor (OECT) is a unique device that shows great promise for sensing in biomedical applications such as monitoring of the integrity of epithelial tissue. It is a label-free sensor that is amenable to low-cost production by roll-to-roll or other printing technologies. Herein, the optimization of a planar OECT for the characterization of barrier tissue is presented. Evaluation of surface coating, gate biocompatibility and performance, and optimization of the geometry of the transistor are highlighted. The conducting polymer poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate), which is used as the active material in the transistor, has the added advantage of allowing significant light transmission compared to traditional electrode materials and thus permits high-quality optical microscopy. The combination of optical and electronic monitoring of cells shown herein provides the opportunity to couple two very complementary techniques to yield a low-cost method for in vitro cell sensing.

Original languageEnglish (US)
Pages (from-to)1210-1216
Number of pages7
JournalChemPhysChem
Volume16
Issue number6
DOIs
StatePublished - Apr 27 2015

Keywords

  • barrier tissue
  • conducting polymers
  • electrochemistry
  • organic electrochemical transistors
  • sensors

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Physical and Theoretical Chemistry

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