Optimizing outcomes with CFTR modulator therapy in the management of cystic fibrosis: A closer look at the role of combination therapy

Importantly, there are more adult patients with cystic fibrosis (CF) now than children. Therapies which correct the underlying pathophysiologic defect in cystic fibrosis are a tremendous advance in treatment. Over 90 percent of patients with cystic fibrosis can be treated with therapies that are already available or, in the case of triple combination therapy, will be available soon.