Organ preservation, ischemia reperfusion injury, and nanotherapeutics in transplantation

Kunal J. Patel; Carl Atkinson; Ann Marie Broome; Satish N. Nadig

doi:10.1007/978-3-319-62142-5_7

Organ preservation, ischemia reperfusion injury, and nanotherapeutics in transplantation

Kunal J. Patel, Carl Atkinson, Ann Marie Broome, Satish N. Nadig^*

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

Over the past 30 years, solid organ transplantation has advanced tremendously in many facets, with great strides made in organ selection and allocation to the monitoring and treatment of rejection. Despite these breakthroughs, organ preservation and chronic rejection rates have remained largely unchanged. Recent trends in translational research have begun to address this issue, and future directions for organ preservation will have far-reaching implications for the field of transplantation as a whole. In this chapter, we will highlight the current trends and innovations in preservation techniques, with a special focus on the role that nanotechnology is playing in this frontier.

Original language	English (US)
Title of host publication	Technological Advances in Organ Transplantation
Publisher	Springer International Publishing
Pages	151-179
Number of pages	29
ISBN (Electronic)	9783319621425
ISBN (Print)	9783319621418
DOIs	https://doi.org/10.1007/978-3-319-62142-5_7
State	Published - May 23 2018
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)
Health Professions(all)
Engineering(all)
Biochemistry, Genetics and Molecular Biology(all)

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10.1007/978-3-319-62142-5_7

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AU - Atkinson, Carl

AU - Broome, Ann Marie

AU - Nadig, Satish N.

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Y1 - 2018/5/23

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AB - Over the past 30 years, solid organ transplantation has advanced tremendously in many facets, with great strides made in organ selection and allocation to the monitoring and treatment of rejection. Despite these breakthroughs, organ preservation and chronic rejection rates have remained largely unchanged. Recent trends in translational research have begun to address this issue, and future directions for organ preservation will have far-reaching implications for the field of transplantation as a whole. In this chapter, we will highlight the current trends and innovations in preservation techniques, with a special focus on the role that nanotechnology is playing in this frontier.

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Organ preservation, ischemia reperfusion injury, and nanotherapeutics in transplantation

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