Organic electrochemical transistors as impedance biosensors

Gregório C. Faria, Duc T. Duong, Alberto Salleo*, Christos A. Polyzoidis, Stergios Logothetidis, Jonathan Rivnay, Roisin Owens, George G. Malliaras

*Corresponding author for this work

Research output: Contribution to journalArticle

20 Scopus citations

Abstract

Interfacing organic electrochemical transistors (OECTs) with biological systems holds considerable promise for building-sensitive biosensors and diagnostic tools. We present a simple model that describes the performance of biosensors in which an OECT is integrated with a biological barrier layer. Using experimentally derived parameters we explore the limits of sensitivity and find that it is dependent on the resistance of the barrier layer. This work provides guidelines on how to optimize biosensors in which OECTs transduce changes in the impedance of biological layers, including lipid bilayer membranes and confluent cell layers.

Original languageEnglish (US)
Pages (from-to)189-194
Number of pages6
JournalMRS Communications
Volume4
Issue number4
DOIs
StatePublished - Sep 25 2014

ASJC Scopus subject areas

  • Materials Science(all)

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    Faria, G. C., Duong, D. T., Salleo, A., Polyzoidis, C. A., Logothetidis, S., Rivnay, J., Owens, R., & Malliaras, G. G. (2014). Organic electrochemical transistors as impedance biosensors. MRS Communications, 4(4), 189-194. https://doi.org/10.1557/mrc.2014.35