Orthopedic Manifestations of In Utero Exposures to Teratogens/Infections

Jill E. Larson

doi:10.1007/978-3-031-11136-5_29

Orthopedic Manifestations of In Utero Exposures to Teratogens/Infections

Jill E. Larson^*

^*Corresponding author for this work

Orthopaedic Surgery

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

Despite improved prenatal access to care and increased knowledge of fetal toxic agents, babies are still born with musculoskeletal deformities that require attention from a pediatric orthopedic surgeon. A teratogenic agent or congenital infection is most likely to cause birth defects during organogenesis between days 15 and 60 of gestation. However, avoiding exposure to teratogens and infections throughout pregnancy is critical to decrease the risk of orthopedic manifestations related to in utero exposures. This chapter will highlight the most common teratogens and congenital infections which can predispose a fetus to orthopedic manifestations such as neural tube defects, limb deformities, and cerebral palsy secondary to premature delivery.

Original language	English (US)
Title of host publication	Orthopaedics for the Newborn and Young Child
Subtitle of host publication	a Practical Clinical Guide
Publisher	Springer International Publishing
Pages	299-308
Number of pages	10
ISBN (Electronic)	9783031111365
ISBN (Print)	9783031111358
DOIs	https://doi.org/10.1007/978-3-031-11136-5_29
State	Published - Jan 1 2022

Keywords

Limb deformities
Neural tube defects
Prenatal
Teratogen
TORCH infections

ASJC Scopus subject areas

General Medicine

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10.1007/978-3-031-11136-5_29

Cite this

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abstract = "Despite improved prenatal access to care and increased knowledge of fetal toxic agents, babies are still born with musculoskeletal deformities that require attention from a pediatric orthopedic surgeon. A teratogenic agent or congenital infection is most likely to cause birth defects during organogenesis between days 15 and 60 of gestation. However, avoiding exposure to teratogens and infections throughout pregnancy is critical to decrease the risk of orthopedic manifestations related to in utero exposures. This chapter will highlight the most common teratogens and congenital infections which can predispose a fetus to orthopedic manifestations such as neural tube defects, limb deformities, and cerebral palsy secondary to premature delivery.",

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AB - Despite improved prenatal access to care and increased knowledge of fetal toxic agents, babies are still born with musculoskeletal deformities that require attention from a pediatric orthopedic surgeon. A teratogenic agent or congenital infection is most likely to cause birth defects during organogenesis between days 15 and 60 of gestation. However, avoiding exposure to teratogens and infections throughout pregnancy is critical to decrease the risk of orthopedic manifestations related to in utero exposures. This chapter will highlight the most common teratogens and congenital infections which can predispose a fetus to orthopedic manifestations such as neural tube defects, limb deformities, and cerebral palsy secondary to premature delivery.

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KW - TORCH infections

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Orthopedic Manifestations of In Utero Exposures to Teratogens/Infections

Abstract

Keywords

ASJC Scopus subject areas

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