Orthostatic tolerance testing in a prospective cohort of adolescents with chronic fatigue syndrome and recovered controls following infectious mononucleosis

Ben Z. Katz*, Julian M. Stewart, Yukiko Shiraishi, Cynthia J. Mears, Renee Taylor

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Chronic fatigue syndrome (CFS) is a complex condition responsible for marked functional impairment. The authors recently reported that 6 months following acute infectious mononucleosis (IM), 13%, of adolescents met criteria for CFS. The authors' objective was to assess standing orthostatic tolerance (SOT) in adolescents with CFS and in controls 6 months following IM. In all, 36 of 39 adolescents diagnosed with CFS 6 months following IM and 43 of 50 recovered controls had SOT testing (SOTT) performed. 2 Analysis was performed to study the relationships between SOTT and the diagnosis of CFS. Adolescents diagnosed with CFS and recovered controls did not differ significantly in age, weight, or body mass index. The authors found that 9 of 36 adolescents with CFS (25%) versus 9 of 43 recovered controls (21%) had an abnormal SOTT, which was not a statistically significant difference. Adolescents who meet criteria for CFS 6 months following IM do not have, as a group, more standing orthostatic intolerance than recovered controls.

Original languageEnglish (US)
Pages (from-to)835-839
Number of pages5
JournalClinical pediatrics
Volume51
Issue number9
DOIs
StatePublished - Sep 2012

Keywords

  • adolescent health
  • chronic fatigue
  • mononucleosis
  • orthostatic tolerance

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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