OSR-1 Nucleic Acids and Proteins

Gregory Beitel (Inventor), Richard I Morimoto (Inventor)

Research output: Patent


OSR-1 Nucleic Acids and Proteins NU 2002-064 Inventors Gregory Beitel Richard Morimoto Aharon Solomon Abstract Northwestern researchers have identified several novel genes that affect dehydration resistance in nematodes. When the expression of the genes is modulated, the survival of parasitic and beneficial nematodes is significantly altered by their change in sensitivity to dry and high salinity environments. Knocking out these genes in beneficial nematodes will enhance their survival, while down-regulation of these genes in parasitic nematodes will decrease their ability to withstand dehydration. Enhancing the survival of beneficial nematodes and decreasing the survival of parasitic nematodes will enhance agricultural production and has enormous implications for improving human and veterinary health. Applications Human and animal health with respect to parasitic nematodes Agriculture productivity with respect to beneficial nematodes Advantages First genes shown to modulate dehydration stress in nematodes and any metazoan species IP Status Issued US Patent No. 7,094,945 Marketing Contact Michael Moore, PhD Invention Manager (p) (847) 491-4645 (e) michaelmoore@northwestern.edu and agriculture productivity.
Original languageEnglish
Patent number7094945
StatePublished - Aug 22 2006

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