Outcome of infections with extended spectrum beta-lactamase producing organisms in children

Ravi Jhaveri; David Bronstein; Janet Sollod; Christina Kitchen; Paul Krogstad

doi:10.1055/s-0035-1556994

Outcome of infections with extended spectrum beta-lactamase producing organisms in children

Ravi Jhaveri^*, David Bronstein, Janet Sollod, Christina Kitchen, Paul Krogstad

^*Corresponding author for this work

Pediatrics

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Infections with organisms producing extended-spectrum beta-lactamases are associated with well established risk factors and poor outcomes in adults, but these are less well defined in children. Our case-control analysis showed that infections with extended-spectrum beta-lactamases producing organisms are linked to prolonged antibiotic usage and are possibly associated with prolonged length of stay and worse overall outcomes in hospitalized children. Efforts to limit the duration and narrow the spectrum of antimicrobial therapy may assist in controlling infections due to these organisms.

Original language	English (US)
Pages (from-to)	229-233
Number of pages	5
Journal	Journal of Pediatric Infectious Diseases
Volume	3
Issue number	4
DOIs	https://doi.org/10.1055/s-0035-1556994
State	Published - Dec 1 2008

Keywords

Antimicrobials
Children
E. coli
ESBL
Extended-spectrum beta-lactamases
K. pneumoniae
Pediatrics

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1055/s-0035-1556994

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abstract = "Infections with organisms producing extended-spectrum beta-lactamases are associated with well established risk factors and poor outcomes in adults, but these are less well defined in children. Our case-control analysis showed that infections with extended-spectrum beta-lactamases producing organisms are linked to prolonged antibiotic usage and are possibly associated with prolonged length of stay and worse overall outcomes in hospitalized children. Efforts to limit the duration and narrow the spectrum of antimicrobial therapy may assist in controlling infections due to these organisms.",

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T1 - Outcome of infections with extended spectrum beta-lactamase producing organisms in children

AU - Jhaveri, Ravi

AU - Bronstein, David

AU - Sollod, Janet

AU - Kitchen, Christina

AU - Krogstad, Paul

PY - 2008/12/1

Y1 - 2008/12/1

N2 - Infections with organisms producing extended-spectrum beta-lactamases are associated with well established risk factors and poor outcomes in adults, but these are less well defined in children. Our case-control analysis showed that infections with extended-spectrum beta-lactamases producing organisms are linked to prolonged antibiotic usage and are possibly associated with prolonged length of stay and worse overall outcomes in hospitalized children. Efforts to limit the duration and narrow the spectrum of antimicrobial therapy may assist in controlling infections due to these organisms.

AB - Infections with organisms producing extended-spectrum beta-lactamases are associated with well established risk factors and poor outcomes in adults, but these are less well defined in children. Our case-control analysis showed that infections with extended-spectrum beta-lactamases producing organisms are linked to prolonged antibiotic usage and are possibly associated with prolonged length of stay and worse overall outcomes in hospitalized children. Efforts to limit the duration and narrow the spectrum of antimicrobial therapy may assist in controlling infections due to these organisms.

KW - Antimicrobials

KW - Children

KW - E. coli

KW - ESBL

KW - Extended-spectrum beta-lactamases

KW - K. pneumoniae

KW - Pediatrics

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JO - Journal of Pediatric Infectious Diseases

JF - Journal of Pediatric Infectious Diseases

IS - 4

ER -

Outcome of infections with extended spectrum beta-lactamase producing organisms in children

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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