Outcomes of bariatric surgery in older versus younger adolescents

Sarah B. Ogle, Lindel C. Dewberry, Todd M. Jenkins, Thomas H. Inge, Megan Kelsey, Matias Bruzoni, Janey S.A. Pratt*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

33 Scopus citations

Abstract

OBJECTIVES: In this report, we compare weight loss, comorbidity resolution, nutritional abnormalities, and quality of life between younger and older adolescents after metabolic and bariatric surgery. METHODS: From March 2007 to December 2011, 242 adolescents (#19 years of age) who underwent bariatric surgery at 5 clinical centers in the United States were enrolled in the prospective, multicenter, long-term outcome study Teen-Longitudinal Assessment of Bariatric Surgery. Outcome data from younger (13-15 years; n = 66) and older (16-19 years; n = 162) study participants were compared. Outcomes included percent BMI change, comorbidity outcomes (hypertension, dyslipidemia, and type 2 diabetes mellitus), nutritional abnormalities, and quality of life over 5 years post surgery. RESULTS: Baseline characteristics, except for age, between the 2 cohorts were similar. No significant differences in frequency of remission of hypertension (P =.84) or dyslipidemia (P =.74) were observed between age groups. Remission of type 2 diabetes mellitus was high in both groups, although statistically higher in older adolescents (relative risk 0.86; P =.046). Weight loss and quality of life were similar in the 2 age groups. Younger adolescents were less likely to develop elevated transferrin (prevalence ratio 0.52; P =.048) and low vitamin D levels (prevalence ratio 0.8; P =.034). CONCLUSIONS: The differences in outcome of metabolic and bariatric surgery between younger and older adolescents were few. These data suggest that younger adolescents with severe obesity should not be denied consideration for surgical therapy on the basis of age alone and that providers should consider adolescents of all ages for surgical therapy for obesity when clinically indicated.

Original languageEnglish (US)
Article numbere2020024182
JournalPediatrics
Volume147
Issue number3
DOIs
StatePublished - Mar 1 2021

Funding

Funded by National Institute of Diabetes and Digestive and Kidney Diseases grants UM1DK072493 (University of Colorado) and UM1DK095710 (University of Cincinnati). The study was also supported by grants UL1TR000077-04 (Cincinnati Children's Hospital Medical Center), UL1RR025755 (Nationwide Children's Hospital), M01-RR00188 (Texas Children's Hospital and Baylor College of Medicine), UL1RR024153 and UL1TR000005 (University of Pittsburgh), and UL1TR000165 (University of Alabama at Birmingham). The sponsors did not participate in the work presented. Funded by the National Institutes of Health (NIH).

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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