Outcomes of pregnancy in adolescents with severe asthma

A. J. Apter, P. A. Greenberger, R. Patterson

Research output: Contribution to journalArticlepeer-review

35 Scopus citations


Asthma in adolescent pregnancies is not rare and may make patient management difficult, especially since mortality from asthma is of particular concern in the adolescent age group. We present a series of 21 pregnant adolescents with severe asthma. During 28 pregnancies, there were 56 exacerbations of asthma, including 22 hospitalizations and 20 emergency room visits. For 18 (64%) of the 28 pregnancies, outpatient systemic corticosteroids were administered, and inhaled corticosteroids were prescribed for 8 (29%). Factors associated with exacerbations included respiratory tract infections (59%) and noncompliance with medial regimens (27%). There were no maternal or fetal deaths or evidence for intrauterine growth retardation. Two infants were premature, with one experiencing acute respiratory distress syndrome. Aggressive treatment of asthma and associated respiratory tract infections, as well as careful ambulatory care, to encourage patient compliance are advisable to achieve a favorable maternal-fetal outcome.

Original languageEnglish (US)
Pages (from-to)2571-2575
Number of pages5
JournalArchives of Internal Medicine
Issue number11
StatePublished - 1989

ASJC Scopus subject areas

  • Internal Medicine

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