Outcomes Research in Cardiovascular Imaging: Report of a Workshop Sponsored by the National Heart, Lung, and Blood Institute

Pamela S. Douglas*, Allen Taylor, Diane Bild, Robert Bonow, Philip Greenland, Michael Lauer, Frank Peacock, James Udelson

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

In July of 2008, the National Heart, Lung, and Blood Institute convened experts in noninvasive cardiovascular imaging, outcomes research, statistics, and clinical trials to develop recommendations for future randomized controlled trials of the use of imaging in: 1) screening the asymptomatic patient for coronary artery disease; 2) assessment of patients with stable angina; 3) identification of acute coronary syndromes in the emergency room; and 4) assessment of heart failure patients with chronic coronary artery disease with reduced left ventricular ejection fraction. This study highlights several possible trial designs for each clinical situation.

Original languageEnglish (US)
Pages (from-to)766-773
Number of pages8
JournalJournal of the American Society of Echocardiography
Volume22
Issue number7
DOIs
StatePublished - Jul 2009

Funding

Dr. Greenland served as a consultant to GE and Toshiba, and received a small honorarium from Pfizer for a role on a Visiting Professor Selection Committee. Dr. Peacock is on the Scientific Advisory Board, or is a consultant or speaker for Abbott, Beckman Coulter, Biosite, Heartscape, Inovise, Inverness, Ortho Clinical Diagnostics, and The Medicine's Company. He has received research grants from Abbott, BAS, Biosite, Brahms, Heartscape, Inovise, Inverness, EKR, and the Medicine's Company. Also, he has an ownership interest in Vital Sensors. Dr. Udelson is co-PI of the ROMICAT-2 trial, sponsored by the American College of Radiology Imaging Network (ACRIN). He has received research funding and has served as a consultant to Lantheus Medical Imaging and Molecular Insight Pharmaceuticals. Drs. Douglas and Taylor are co-first authors. Reviewers for this article are: Stephan Achenbach, MD, Associate Editor, JACC: Cardiovascular Imaging; Thomas Marwick, MBBS, PhD, Associate Editor, JACC: Cardiovascular Imaging; Christopher Kramer, MD, Associate Editor, JACC: Cardiovascular Imaging; Vasken Dilsizian, MD, Associate Editor, JACC: Cardiovascular Imaging.

Keywords

  • Cardiovascular imaging
  • Chest pain diagnosis
  • Clinical trials

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging

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