Overcoming the blood-brain barrier with an implantable ultrasound device

Adam M. Sonabend, Roger Stupp*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Ultrasound-based blood-brain barrier disruption enhances drug delivery. To bypass the human skull, an implantable ultrasound emitter was developed, and proven safe and feasible in a first-in-human trial. Next development steps aim for larger field of disruption, quantification of drug levels, use of various drugs, and ultimately a pivotal trial demonstrating improved outcome.

Original languageEnglish (US)
Pages (from-to)3750-3752
Number of pages3
JournalClinical Cancer Research
Volume25
Issue number13
DOIs
StatePublished - 2019

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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