Packed red blood cell age does not impact adverse events or outcomes after subarachnoid haemorrhage

A. M. Naidech*, S. M. Liebling, I. M. Duran, M. L. Ault

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Objectives: To determine if the age of packed red blood cells (PRBCs) is associated with adverse events or outcomes in patients with subarachnoid haemorrhage (SAH). Aim: Analyse data on PRBC age to complications and outcomes in patients with SAH. Background: Patients who receive a PRBC transfusion after SAH have a higher rate of complications, and older PRBC age may be responsible for this. Methods/Materials: We prospectively recorded clinical and demographic data, acute adverse effects related to transfusion, major hospital events, radiographic cerebral infarction, PRBC age and outcomes in 119 patients with SAH who received a PRBC transfusion. Patients were followed for outcomes at 14 days or discharge, 28 days and 3 months with the modified Rankin scale (a measure of neurologic function). Results: In 241 PRBC transfusions, there was new fever in 36 (15%), hypotension in 23 (10%), pulmonary oedema or symptomatic respiratory distress in 5 (2%) and rash in 1 (1%). Age of PRBCs administered was not associated with vasospasm, cerebral infarction, acute adverse events or outcomes (P > 0·1 for all). Conclusions: In this small registry of patients with SAH, the age of transfused PRBCs was not associated with adverse events or outcomes.

Original languageEnglish (US)
Pages (from-to)130-133
Number of pages4
JournalTransfusion Medicine
Volume21
Issue number2
DOIs
StatePublished - Apr 1 2011

Keywords

  • Anaemia
  • Cerebral infarction
  • Outcomes
  • Subarachnoid haemorrhage
  • Transfusion

ASJC Scopus subject areas

  • Hematology

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