TY - JOUR
T1 - Pain Measurement in Children with Functional Abdominal Pain
AU - Lavigne, John V.
AU - Saps, Miguel
PY - 2016/4/1
Y1 - 2016/4/1
N2 - Functional abdominal pain (FAP) occurs frequently in pediatric patients. Lacking clear biomarkers, clinicians and researchers must rely on patient reports of pain intensity. Presently, there are challenges affecting our ability to use existing measures of self-reported pediatric pain intensity. This report discusses those challenges, finding that: (a) inter-rater agreement of children’s pain intensity is generally low; (b) typically used approaches to measuring outcomes may yield high levels of unreliable reports of improvement; (c) a distribution-based approach involving the calculation of a reliable change index can produce results that classify individuals as improved reliably, but this approach needs to be combined with another approach that ensures the findings will be clinically meaningful as well; (d) clinical trials for FAP rarely report findings about how many individuals improve in a statistically reliable, clinically meaningful manner; and (e) more information about the test–retest reliability of commonly used measures is needed to accurately gauge treatment-related improvement.
AB - Functional abdominal pain (FAP) occurs frequently in pediatric patients. Lacking clear biomarkers, clinicians and researchers must rely on patient reports of pain intensity. Presently, there are challenges affecting our ability to use existing measures of self-reported pediatric pain intensity. This report discusses those challenges, finding that: (a) inter-rater agreement of children’s pain intensity is generally low; (b) typically used approaches to measuring outcomes may yield high levels of unreliable reports of improvement; (c) a distribution-based approach involving the calculation of a reliable change index can produce results that classify individuals as improved reliably, but this approach needs to be combined with another approach that ensures the findings will be clinically meaningful as well; (d) clinical trials for FAP rarely report findings about how many individuals improve in a statistically reliable, clinically meaningful manner; and (e) more information about the test–retest reliability of commonly used measures is needed to accurately gauge treatment-related improvement.
KW - Abdominal pain
KW - Clinically significant change (CSC)
KW - Functional abdominal pain (FAP)
KW - Pain
KW - Patient-reported outcome (PRO)
UR - http://www.scopus.com/inward/record.url?scp=84963852900&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84963852900&partnerID=8YFLogxK
U2 - 10.1007/s11894-016-0493-1
DO - 10.1007/s11894-016-0493-1
M3 - Review article
C2 - 27079570
AN - SCOPUS:84963852900
SN - 1522-8037
VL - 18
JO - Current gastroenterology reports
JF - Current gastroenterology reports
IS - 4
M1 - 20
ER -