Pancreatic adenocarcinoma, version 2.2017

Clinical practice guidelines in Oncology

Margaret A. Tempero, Mokenge P. Malafa, Mahmoud Al-Hawary, Horacio Asbun, Andrew Bain, Stephen W. Behrman, B. Al Benson, Ellen Binder, Dana B. Cardin, Charles Cha, E. Gabriela Chiorean, Vincent Chung, Brian Czito, Mary Dillhoff, Efrat Dotan, Cristina R. Ferrone, Jeffrey Hardacre, William G. Hawkins, Joseph Herman, Andrew H. Ko & 16 others Srinadh Komanduri, Albert Koong, Noelle LoConte, Andrew M. Lowy, Cassadie Moravek, Eric K. Nakakura, Eileen M. O'Reilly, Jorge Obando, Sushanth Reddy, Courtney Scaife, Sarah Thayer, Colin D. Weekes, Robert A. Wolff, Brian M. Wolpin, Jennifer Burns, Susan Darlow

Research output: Contribution to journalReview article

198 Citations (Scopus)

Abstract

Ductal adenocarcinoma and its variants account for most pancreatic malignancies. High-quality multiphase imaging can help to preoperatively distinguish between patients eligible for resection with curative intent and those with unresect-able disease. Systemic therapy is used in the neoadjuvant or adjuvant pancreatic cancer setting, as well as in the management of locally advanced unresectable and metastatic disease. Clinical trials are critical for making progress in treatment of pancreatic cancer. The NCCN Guidelines for Pancreatic Adeno-carcinoma focus on diagnosis and treatment with systemic therapy, radiation therapy, and surgical resection.

Original languageEnglish (US)
Pages (from-to)1028-1061
Number of pages34
JournalJNCCN Journal of the National Comprehensive Cancer Network
Volume15
Issue number8
DOIs
StatePublished - Aug 1 2017

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Practice Guidelines
Adenocarcinoma
Pancreatic Neoplasms
Therapeutics
Radiotherapy
Clinical Trials
Guidelines
Neoplasms

ASJC Scopus subject areas

  • Oncology

Cite this

Tempero, M. A., Malafa, M. P., Al-Hawary, M., Asbun, H., Bain, A., Behrman, S. W., ... Darlow, S. (2017). Pancreatic adenocarcinoma, version 2.2017: Clinical practice guidelines in Oncology. JNCCN Journal of the National Comprehensive Cancer Network, 15(8), 1028-1061. https://doi.org/10.6004/jnccn.2017.0131
Tempero, Margaret A. ; Malafa, Mokenge P. ; Al-Hawary, Mahmoud ; Asbun, Horacio ; Bain, Andrew ; Behrman, Stephen W. ; Al Benson, B. ; Binder, Ellen ; Cardin, Dana B. ; Cha, Charles ; Chiorean, E. Gabriela ; Chung, Vincent ; Czito, Brian ; Dillhoff, Mary ; Dotan, Efrat ; Ferrone, Cristina R. ; Hardacre, Jeffrey ; Hawkins, William G. ; Herman, Joseph ; Ko, Andrew H. ; Komanduri, Srinadh ; Koong, Albert ; LoConte, Noelle ; Lowy, Andrew M. ; Moravek, Cassadie ; Nakakura, Eric K. ; O'Reilly, Eileen M. ; Obando, Jorge ; Reddy, Sushanth ; Scaife, Courtney ; Thayer, Sarah ; Weekes, Colin D. ; Wolff, Robert A. ; Wolpin, Brian M. ; Burns, Jennifer ; Darlow, Susan. / Pancreatic adenocarcinoma, version 2.2017 : Clinical practice guidelines in Oncology. In: JNCCN Journal of the National Comprehensive Cancer Network. 2017 ; Vol. 15, No. 8. pp. 1028-1061.
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abstract = "Ductal adenocarcinoma and its variants account for most pancreatic malignancies. High-quality multiphase imaging can help to preoperatively distinguish between patients eligible for resection with curative intent and those with unresect-able disease. Systemic therapy is used in the neoadjuvant or adjuvant pancreatic cancer setting, as well as in the management of locally advanced unresectable and metastatic disease. Clinical trials are critical for making progress in treatment of pancreatic cancer. The NCCN Guidelines for Pancreatic Adeno-carcinoma focus on diagnosis and treatment with systemic therapy, radiation therapy, and surgical resection.",
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Tempero, MA, Malafa, MP, Al-Hawary, M, Asbun, H, Bain, A, Behrman, SW, Al Benson, B, Binder, E, Cardin, DB, Cha, C, Chiorean, EG, Chung, V, Czito, B, Dillhoff, M, Dotan, E, Ferrone, CR, Hardacre, J, Hawkins, WG, Herman, J, Ko, AH, Komanduri, S, Koong, A, LoConte, N, Lowy, AM, Moravek, C, Nakakura, EK, O'Reilly, EM, Obando, J, Reddy, S, Scaife, C, Thayer, S, Weekes, CD, Wolff, RA, Wolpin, BM, Burns, J & Darlow, S 2017, 'Pancreatic adenocarcinoma, version 2.2017: Clinical practice guidelines in Oncology', JNCCN Journal of the National Comprehensive Cancer Network, vol. 15, no. 8, pp. 1028-1061. https://doi.org/10.6004/jnccn.2017.0131

Pancreatic adenocarcinoma, version 2.2017 : Clinical practice guidelines in Oncology. / Tempero, Margaret A.; Malafa, Mokenge P.; Al-Hawary, Mahmoud; Asbun, Horacio; Bain, Andrew; Behrman, Stephen W.; Al Benson, B.; Binder, Ellen; Cardin, Dana B.; Cha, Charles; Chiorean, E. Gabriela; Chung, Vincent; Czito, Brian; Dillhoff, Mary; Dotan, Efrat; Ferrone, Cristina R.; Hardacre, Jeffrey; Hawkins, William G.; Herman, Joseph; Ko, Andrew H.; Komanduri, Srinadh; Koong, Albert; LoConte, Noelle; Lowy, Andrew M.; Moravek, Cassadie; Nakakura, Eric K.; O'Reilly, Eileen M.; Obando, Jorge; Reddy, Sushanth; Scaife, Courtney; Thayer, Sarah; Weekes, Colin D.; Wolff, Robert A.; Wolpin, Brian M.; Burns, Jennifer; Darlow, Susan.

In: JNCCN Journal of the National Comprehensive Cancer Network, Vol. 15, No. 8, 01.08.2017, p. 1028-1061.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Pancreatic adenocarcinoma, version 2.2017

T2 - Clinical practice guidelines in Oncology

AU - Tempero, Margaret A.

AU - Malafa, Mokenge P.

AU - Al-Hawary, Mahmoud

AU - Asbun, Horacio

AU - Bain, Andrew

AU - Behrman, Stephen W.

AU - Al Benson, B.

AU - Binder, Ellen

AU - Cardin, Dana B.

AU - Cha, Charles

AU - Chiorean, E. Gabriela

AU - Chung, Vincent

AU - Czito, Brian

AU - Dillhoff, Mary

AU - Dotan, Efrat

AU - Ferrone, Cristina R.

AU - Hardacre, Jeffrey

AU - Hawkins, William G.

AU - Herman, Joseph

AU - Ko, Andrew H.

AU - Komanduri, Srinadh

AU - Koong, Albert

AU - LoConte, Noelle

AU - Lowy, Andrew M.

AU - Moravek, Cassadie

AU - Nakakura, Eric K.

AU - O'Reilly, Eileen M.

AU - Obando, Jorge

AU - Reddy, Sushanth

AU - Scaife, Courtney

AU - Thayer, Sarah

AU - Weekes, Colin D.

AU - Wolff, Robert A.

AU - Wolpin, Brian M.

AU - Burns, Jennifer

AU - Darlow, Susan

PY - 2017/8/1

Y1 - 2017/8/1

N2 - Ductal adenocarcinoma and its variants account for most pancreatic malignancies. High-quality multiphase imaging can help to preoperatively distinguish between patients eligible for resection with curative intent and those with unresect-able disease. Systemic therapy is used in the neoadjuvant or adjuvant pancreatic cancer setting, as well as in the management of locally advanced unresectable and metastatic disease. Clinical trials are critical for making progress in treatment of pancreatic cancer. The NCCN Guidelines for Pancreatic Adeno-carcinoma focus on diagnosis and treatment with systemic therapy, radiation therapy, and surgical resection.

AB - Ductal adenocarcinoma and its variants account for most pancreatic malignancies. High-quality multiphase imaging can help to preoperatively distinguish between patients eligible for resection with curative intent and those with unresect-able disease. Systemic therapy is used in the neoadjuvant or adjuvant pancreatic cancer setting, as well as in the management of locally advanced unresectable and metastatic disease. Clinical trials are critical for making progress in treatment of pancreatic cancer. The NCCN Guidelines for Pancreatic Adeno-carcinoma focus on diagnosis and treatment with systemic therapy, radiation therapy, and surgical resection.

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U2 - 10.6004/jnccn.2017.0131

DO - 10.6004/jnccn.2017.0131

M3 - Review article

VL - 15

SP - 1028

EP - 1061

JO - Journal of the National Comprehensive Cancer Network : JNCCN

JF - Journal of the National Comprehensive Cancer Network : JNCCN

SN - 1540-1405

IS - 8

ER -