Pancreatic blastomatous tumor in a child responding to therapy used for hepatoblastoma: Case report and review of the literature

Elaine R. Morgan*, John H. Perryman, Marleta Reynolds, Frank J. Gonzalez-Crussi

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

A case is reported of a 7-year-old girl diagnosed with initially inoperable metastatic embryonic pancreatic tumor, which showed a significant clinical response to chemotherapeutic agents commonly used to treat hepatoblastoma. This regimen was selected because certain histologic features of the tumor demonstrated characteristics seen in hepatic tissue. After two courses of chemotherapy (cis-platinum and adriamycin), there was a significant reduction of the primary mass, and it was completely resected, although the tumor subsequently recurred in the metastatic, unoperated site. The embryologic relationship between the tumor in this patient and hepatoblastoma, as well as the literature concerning treatment in pediatric pancreatoblastic tumors are reviewed. Complete eradication of tumor appears to be necessary for cure.

Original languageEnglish (US)
Pages (from-to)284-292
Number of pages9
JournalMedical and Pediatric Oncology
Volume26
Issue number4
DOIs
StatePublished - Apr 1 1996

Keywords

  • chemotherapy
  • embryology
  • pancreatic tumors
  • pancreatoblastoma
  • pediatric oncology

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Oncology
  • Cancer Research

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