Paroxysmal Nocturnal Hemoglobinuria Presenting As Recurrent Hemolytic Uremic Syndrome

Morris Kletzel; Watson C. Arnold; Daisilee H. Berry

doi:10.1177/000992288702600613

Paroxysmal Nocturnal Hemoglobinuria Presenting As Recurrent Hemolytic Uremic Syndrome

Morris Kletzel, Watson C. Arnold^*, Daisilee H. Berry

^*Corresponding author for this work

Pediatrics

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Paroxysmal nocturnal hemoglobinuria (PNH) may present with acute anemia, thrombocytopenia and, if hemoglobin nephropathy or dehydration is present, azotemia. Thus PNH may be confused with the hemolytic uremic syndrome (HUS). Recurrent episodes, though common in PNH, are unusual in HUS. A positive acid hemolysis test can be used to differentiate between the two diseases.

Original language	English (US)
Pages (from-to)	319-320
Number of pages	2
Journal	Clinical pediatrics
Volume	26
Issue number	6
DOIs	https://doi.org/10.1177/000992288702600613
State	Published - Jun 1987

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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title = "Paroxysmal Nocturnal Hemoglobinuria Presenting As Recurrent Hemolytic Uremic Syndrome",

abstract = "Paroxysmal nocturnal hemoglobinuria (PNH) may present with acute anemia, thrombocytopenia and, if hemoglobin nephropathy or dehydration is present, azotemia. Thus PNH may be confused with the hemolytic uremic syndrome (HUS). Recurrent episodes, though common in PNH, are unusual in HUS. A positive acid hemolysis test can be used to differentiate between the two diseases.",

author = "Morris Kletzel and Arnold, {Watson C.} and Berry, {Daisilee H.}",

year = "1987",

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AU - Berry, Daisilee H.

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N2 - Paroxysmal nocturnal hemoglobinuria (PNH) may present with acute anemia, thrombocytopenia and, if hemoglobin nephropathy or dehydration is present, azotemia. Thus PNH may be confused with the hemolytic uremic syndrome (HUS). Recurrent episodes, though common in PNH, are unusual in HUS. A positive acid hemolysis test can be used to differentiate between the two diseases.

AB - Paroxysmal nocturnal hemoglobinuria (PNH) may present with acute anemia, thrombocytopenia and, if hemoglobin nephropathy or dehydration is present, azotemia. Thus PNH may be confused with the hemolytic uremic syndrome (HUS). Recurrent episodes, though common in PNH, are unusual in HUS. A positive acid hemolysis test can be used to differentiate between the two diseases.

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Paroxysmal Nocturnal Hemoglobinuria Presenting As Recurrent Hemolytic Uremic Syndrome

Abstract

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