Passively aligned 100-port micro-fluidic connector

Craig R. Forest; Michael J. Beltran; Ian W. Hunter

Passively aligned 100-port micro-fluidic connector

Craig R. Forest, Michael J. Beltran, Ian W. Hunter

Mechanical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Scopus citations

Abstract

Widespread application of micro-fluidic systems has been hindered by the challenge of repeatable, accurate interfacing between integrated channels or wells and external loading, detecting, or stimulating devices. We are developing a repeatable, accurate, 100-port micro-fluidic connector to interface to a 100 capillary array. The capillaries are passively aligned for connection with a combination of precision guide pins and conical tapered holes, and sealed with a PDMS layer after insertion. Using the connector device, an array of 100 loosely-assembled capillaries with 1 mm spacing can be aligned to 20 μm radial accuracy and high repeatability, with only 5% failure after 10,000 insertions. We have confirmed electrical and fluidic connectivity as well. This device can be simply manufactured and adapted for numerous micro-fluidic interface applications.

Original language	English (US)
Title of host publication	Proceedings of the 21st Annual ASPE Meeting, ASPE 2006
State	Published - Dec 1 2006
Event	21st Annual Meeting of the American Society for Precision Engineering, ASPE 2006 - Monterey, CA, United States Duration: Oct 15 2006 → Oct 20 2006

Publication series

Name	Proceedings of the 21st Annual ASPE Meeting, ASPE 2006

Other

Other	21st Annual Meeting of the American Society for Precision Engineering, ASPE 2006
Country/Territory	United States
City	Monterey, CA
Period	10/15/06 → 10/20/06

ASJC Scopus subject areas

Mechanical Engineering

Cite this

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title = "Passively aligned 100-port micro-fluidic connector",

abstract = "Widespread application of micro-fluidic systems has been hindered by the challenge of repeatable, accurate interfacing between integrated channels or wells and external loading, detecting, or stimulating devices. We are developing a repeatable, accurate, 100-port micro-fluidic connector to interface to a 100 capillary array. The capillaries are passively aligned for connection with a combination of precision guide pins and conical tapered holes, and sealed with a PDMS layer after insertion. Using the connector device, an array of 100 loosely-assembled capillaries with 1 mm spacing can be aligned to 20 μm radial accuracy and high repeatability, with only 5% failure after 10,000 insertions. We have confirmed electrical and fluidic connectivity as well. This device can be simply manufactured and adapted for numerous micro-fluidic interface applications.",

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year = "2006",

month = dec,

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AU - Beltran, Michael J.

AU - Hunter, Ian W.

PY - 2006/12/1

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N2 - Widespread application of micro-fluidic systems has been hindered by the challenge of repeatable, accurate interfacing between integrated channels or wells and external loading, detecting, or stimulating devices. We are developing a repeatable, accurate, 100-port micro-fluidic connector to interface to a 100 capillary array. The capillaries are passively aligned for connection with a combination of precision guide pins and conical tapered holes, and sealed with a PDMS layer after insertion. Using the connector device, an array of 100 loosely-assembled capillaries with 1 mm spacing can be aligned to 20 μm radial accuracy and high repeatability, with only 5% failure after 10,000 insertions. We have confirmed electrical and fluidic connectivity as well. This device can be simply manufactured and adapted for numerous micro-fluidic interface applications.

AB - Widespread application of micro-fluidic systems has been hindered by the challenge of repeatable, accurate interfacing between integrated channels or wells and external loading, detecting, or stimulating devices. We are developing a repeatable, accurate, 100-port micro-fluidic connector to interface to a 100 capillary array. The capillaries are passively aligned for connection with a combination of precision guide pins and conical tapered holes, and sealed with a PDMS layer after insertion. Using the connector device, an array of 100 loosely-assembled capillaries with 1 mm spacing can be aligned to 20 μm radial accuracy and high repeatability, with only 5% failure after 10,000 insertions. We have confirmed electrical and fluidic connectivity as well. This device can be simply manufactured and adapted for numerous micro-fluidic interface applications.

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T3 - Proceedings of the 21st Annual ASPE Meeting, ASPE 2006

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ER -

Passively aligned 100-port micro-fluidic connector

Abstract

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ASJC Scopus subject areas

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