Paternal age effect of YY aneuploidy in human sperm, as assessed by fluorescence in situ hybridization

B. Kinakin, A. Rademaker, R. Martin*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

63 Scopus citations

Abstract

Sperm samples were collected from 18 healthy men of various ages. Multicolor FISH was performed on each sample, using probes for the sex chromosomes and chromosome 1. A minimum of 10,000 sperm per donor was analyzed. The Pearson correlation coefficient was used to determine if there was an association between donor age and disomy frequency for the sex chromosomes.

Original languageEnglish (US)
Pages (from-to)116-119
Number of pages4
JournalCytogenetic and Genome Research
Volume78
Issue number2
DOIs
StatePublished - Jan 1 1997

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Genetics(clinical)

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