Paternal vs. Maternal Factors in Childhood Atopic Dermatitis

Alexandra R. Vaughn; Raja K. Sivamani; Peter A. Lio; Vivian Y. Shi

doi:10.1097/DER.0000000000000305

Paternal vs. Maternal Factors in Childhood Atopic Dermatitis

Alexandra R. Vaughn, Raja K. Sivamani, Peter A. Lio, Vivian Y. Shi^*

^*Corresponding author for this work

Dermatology

Research output: Contribution to journal › Review article › peer-review

7 Scopus citations

Abstract

Atopic dermatitis (AD) is a common inflammatory skin disease that chronically affects children and adults worldwide. Environmental exposures, heritable factors, immune dysregulation, and skin barrier malfunction all contribute to the multifactorial nature of AD. It is known that maternal and paternal influences are important predictors for the risk of AD in offspring. This review examines and compares the evidence and mechanisms behind specific maternal and paternal factors that may contribute to the pathogenesis of AD.

Original language	English (US)
Pages (from-to)	241-245
Number of pages	5
Journal	Dermatitis
Volume	28
Issue number	4
DOIs	https://doi.org/10.1097/DER.0000000000000305
State	Published - Jul 1 2017

ASJC Scopus subject areas

Immunology and Allergy
Dermatology

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10.1097/DER.0000000000000305

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abstract = "Atopic dermatitis (AD) is a common inflammatory skin disease that chronically affects children and adults worldwide. Environmental exposures, heritable factors, immune dysregulation, and skin barrier malfunction all contribute to the multifactorial nature of AD. It is known that maternal and paternal influences are important predictors for the risk of AD in offspring. This review examines and compares the evidence and mechanisms behind specific maternal and paternal factors that may contribute to the pathogenesis of AD.",

author = "Vaughn, {Alexandra R.} and Sivamani, {Raja K.} and Lio, {Peter A.} and Shi, {Vivian Y.}",

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AU - Vaughn, Alexandra R.

AU - Sivamani, Raja K.

AU - Lio, Peter A.

AU - Shi, Vivian Y.

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N2 - Atopic dermatitis (AD) is a common inflammatory skin disease that chronically affects children and adults worldwide. Environmental exposures, heritable factors, immune dysregulation, and skin barrier malfunction all contribute to the multifactorial nature of AD. It is known that maternal and paternal influences are important predictors for the risk of AD in offspring. This review examines and compares the evidence and mechanisms behind specific maternal and paternal factors that may contribute to the pathogenesis of AD.

AB - Atopic dermatitis (AD) is a common inflammatory skin disease that chronically affects children and adults worldwide. Environmental exposures, heritable factors, immune dysregulation, and skin barrier malfunction all contribute to the multifactorial nature of AD. It is known that maternal and paternal influences are important predictors for the risk of AD in offspring. This review examines and compares the evidence and mechanisms behind specific maternal and paternal factors that may contribute to the pathogenesis of AD.

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Paternal vs. Maternal Factors in Childhood Atopic Dermatitis

Abstract

ASJC Scopus subject areas

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