Pathologic findings in allergic aspergillus sinusitis. A newly recognized form of sinusitis

A. L A Katzenstein, S. R. Sale, P. A. Greenberger

Research output: Contribution to journalArticle

103 Scopus citations

Abstract

The pathologic findings are described in seven cases of allergic aspergillus sinusitis, a newly recognized form of sinusitis. Grossly, the sinuses are filled with firm, white-tan mucoid material. Microscopically this material consists of mucin-containing numerous eosinophils, sloughed respiratory epithelial cells, cellular debris, Charcot-Leyden crystals, and scattered fungal hyphae resembling aspergillus species. This histologic appearance is identical to mucoid impaction occurring in bronchi in allergic bronchopulmonary aspergillosis. Allergic aspergillus sinusitis and allergic bronchopulmonary aspergillosis may represent different manifestations of aspergillus hypersensitivity in the respiratory tract. Implications for treatment of allergic aspergillus sinusitis and a possible relationship between it and allergic bronchopulmonary aspergillosis are discussed.

Original languageEnglish (US)
Pages (from-to)439-443
Number of pages5
JournalAmerican Journal of Surgical Pathology
Volume7
Issue number5
DOIs
StatePublished - 1983

ASJC Scopus subject areas

  • Anatomy
  • Surgery
  • Pathology and Forensic Medicine

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