Pathology in Patients with Chronic Liver Disease: A Practical Approach to Liver Biopsy Interpretation in Patients with Acute and Chronic Liver Diseases

Audrey Deeken-Draisey; Sambasiva M. Rao; Guang Yu Yang

doi:10.1016/j.cld.2020.04.001

Pathology in Patients with Chronic Liver Disease: A Practical Approach to Liver Biopsy Interpretation in Patients with Acute and Chronic Liver Diseases

Audrey Deeken-Draisey, Sambasiva M. Rao, Guang Yu Yang^*

^*Corresponding author for this work

Pathology

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

Abstract

Liver biopsy and histologic examination are the mainstay for diagnosing liver diseases, despite advances in imaging and molecular procedures. Liver biopsy can provide useful information regarding the structural integrity and type and degree of injury, disease activity, response to treatment, progression of disease and degree/staging of fibrosis. Liver biopsies evaluate acute and chronic liver diseases, and mass-forming lesions. The role of the pathologist is to integrate clinical, serologic, and biochemical data with morphologic changes and provide a comprehensive diagnosis. This review focuses on basic principles necessary for proper interpretation of liver biopsy specimens in patients with chronic liver disease.

Original language	English (US)
Pages (from-to)	361-372
Number of pages	12
Journal	Clinics in liver disease
Volume	24
Issue number	3
DOIs	https://doi.org/10.1016/j.cld.2020.04.001
State	Published - Aug 2020

Keywords

Acute liver disease
Chronic liver disease
Liver biopsy
Pathology
Staging
Treatment

ASJC Scopus subject areas

Hepatology

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10.1016/j.cld.2020.04.001

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title = "Pathology in Patients with Chronic Liver Disease: A Practical Approach to Liver Biopsy Interpretation in Patients with Acute and Chronic Liver Diseases",

abstract = "Liver biopsy and histologic examination are the mainstay for diagnosing liver diseases, despite advances in imaging and molecular procedures. Liver biopsy can provide useful information regarding the structural integrity and type and degree of injury, disease activity, response to treatment, progression of disease and degree/staging of fibrosis. Liver biopsies evaluate acute and chronic liver diseases, and mass-forming lesions. The role of the pathologist is to integrate clinical, serologic, and biochemical data with morphologic changes and provide a comprehensive diagnosis. This review focuses on basic principles necessary for proper interpretation of liver biopsy specimens in patients with chronic liver disease.",

keywords = "Acute liver disease, Chronic liver disease, Liver biopsy, Pathology, Staging, Treatment",

author = "Audrey Deeken-Draisey and Rao, {Sambasiva M.} and Yang, {Guang Yu}",

note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",

year = "2020",

month = aug,

doi = "10.1016/j.cld.2020.04.001",

language = "English (US)",

volume = "24",

pages = "361--372",

journal = "Clinics in liver disease",

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publisher = "W.B. Saunders Ltd",

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TY - JOUR

T1 - Pathology in Patients with Chronic Liver Disease

T2 - A Practical Approach to Liver Biopsy Interpretation in Patients with Acute and Chronic Liver Diseases

AU - Deeken-Draisey, Audrey

AU - Rao, Sambasiva M.

AU - Yang, Guang Yu

PY - 2020/8

Y1 - 2020/8

N2 - Liver biopsy and histologic examination are the mainstay for diagnosing liver diseases, despite advances in imaging and molecular procedures. Liver biopsy can provide useful information regarding the structural integrity and type and degree of injury, disease activity, response to treatment, progression of disease and degree/staging of fibrosis. Liver biopsies evaluate acute and chronic liver diseases, and mass-forming lesions. The role of the pathologist is to integrate clinical, serologic, and biochemical data with morphologic changes and provide a comprehensive diagnosis. This review focuses on basic principles necessary for proper interpretation of liver biopsy specimens in patients with chronic liver disease.

AB - Liver biopsy and histologic examination are the mainstay for diagnosing liver diseases, despite advances in imaging and molecular procedures. Liver biopsy can provide useful information regarding the structural integrity and type and degree of injury, disease activity, response to treatment, progression of disease and degree/staging of fibrosis. Liver biopsies evaluate acute and chronic liver diseases, and mass-forming lesions. The role of the pathologist is to integrate clinical, serologic, and biochemical data with morphologic changes and provide a comprehensive diagnosis. This review focuses on basic principles necessary for proper interpretation of liver biopsy specimens in patients with chronic liver disease.

KW - Acute liver disease

KW - Chronic liver disease

KW - Liver biopsy

KW - Pathology

KW - Staging

KW - Treatment

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U2 - 10.1016/j.cld.2020.04.001

DO - 10.1016/j.cld.2020.04.001

M3 - Review article

C2 - 32620277

AN - SCOPUS:85084516113

SN - 1089-3261

VL - 24

SP - 361

EP - 372

JO - Clinics in liver disease

JF - Clinics in liver disease

IS - 3

ER -

Pathology in Patients with Chronic Liver Disease: A Practical Approach to Liver Biopsy Interpretation in Patients with Acute and Chronic Liver Diseases

Abstract

Keywords

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