Patient-specific flexible and stretchable devices for cardiac diagnostics and therapy

Sarah R. Gutbrod, Matthew S. Sulkin, John A. Rogers, Igor R. Efimov*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

52 Scopus citations


Advances in material science techniques and pioneering circuit designs have led to the development of electronic membranes that can form intimate contacts with biological tissues. In this review, we present the range of geometries, sensors, and actuators available for custom configurations of electronic membranes in cardiac applications. Additionally, we highlight the desirable mechanics achieved by such devices that allow the circuits and substrates to deform with the beating heart. These devices unlock opportunities to collect continuous data on the electrical, metabolic, and mechanical state of the heart as well as a platform on which to develop high definition therapeutics.

Original languageEnglish (US)
Pages (from-to)244-251
Number of pages8
JournalProgress in Biophysics and Molecular Biology
Issue number2-3
StatePublished - Aug 1 2014


  • Bioelectronics
  • Imaging
  • Physiology

ASJC Scopus subject areas

  • Molecular Biology
  • Biophysics


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