Patterned electrospun nanofiber matrices via localized dissolution: Potential for guided tissue formation

Chao Jia*, Dou Yu, Marven Lamarre, Philip L. Leopold, Yang D. Teng, Hongjun Wang

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

43 Scopus citations

Abstract

(Figure Presented). With the assistance of an ink-jet printer, solvent (the "ink") can be controllably and reproducibly printed onto electrospun nanofiber meshes (the "paper") to generate various micropatterns and subsequently guide distinct cellular organization and phenotype expression. In combination with the nanofiber-assisted layer-by-layer cell assembly, the patterned electrospun meshes will define an instructive microenvironment for guided tissue formation.

Original languageEnglish (US)
Pages (from-to)8192-8197
Number of pages6
JournalAdvanced Materials
Volume26
Issue number48
DOIs
StatePublished - Dec 2014

Keywords

  • Electrospinning
  • Guided tissue formation
  • Localized nanofiber dissolution
  • Micropatterns

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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