Pearls and Pitfalls in Evidence Based Medicine: What We've Learned About Outcomes Research in Spine Surgery

Adam M. Pearson*, James Neil Weinstein

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Spine care has become increasingly evidence-based. The investigators who have generated this evidence have learned important lessons that should help guide future trials: 1. Patients will agree to enroll in studies and to be randomized; 2. Patients will crossover between treatment arms if it is an option; 3. Observational studies can provide the best answers to some questions; 4. High quality clinical research is extremely expensive and work-intensive; 5. High quality spine research is needed now more than ever. This paper reviews these issues as they have arisen in recent clinical studies.

Original languageEnglish (US)
Pages (from-to)264-267
Number of pages4
JournalSeminars in Spine Surgery
Volume21
Issue number4
DOIs
StatePublished - Dec 2009

Keywords

  • clinical trials
  • crossover
  • spine surgery

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

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