Pediatric anthrax clinical management

John S. Bradley, Steven E. Krug, William A. Bower, Amanda C. Cohn, Dana Meaney-Delman, Andrew T. Pavia, Sarita Chung, Daniel B. Fagbuyi, Margaret Fisher, Scott Needle, David J. Schonfeld, John Alexander, Andrew Garrett, Georgina Peacock, Sally Phillips, Erica Radden, David Siegel, Laura Aird, Sean Diederich, Tamar HaroMichael Thomas Brady, Carrie Lynn Byington, H. Dele Davies, Kathryn M. Edwards, Mary Anne Jackson, Yvonne Aida Maldonado, Dennis Murray, Walter A. Orenstein, Mobeen H. Rathore, Mark H. Sawyer, Gordon E. Schutze, Rodney E. Willoughby, Theoklis Zaoutis, Henry H. Bernstein, David Winston Kimberlin, Sarah S. Long, H. Cody Meissner, Marc Fischer, Bruce Gellin, Richard L. Gorman, Lucia Lee, R. Douglas Pratt, Jennifer S. Read, Joan Robinson, Marco Aurelio Palazzi Safadi, Jane Seward, Geoffrey Simon, Jeffrey Robert Starke, Tina Quanbee Tan, Jennifer Frantz

Research output: Contribution to journalArticle

21 Scopus citations

Abstract

Anthrax is a zoonotic disease caused by Bacillus anthracis, which has multiple routes of infection in humans, manifesting in different initial presentations of disease. Because B anthracis has the potential to be used as a biological weapon and can rapidly progress to systemic anthrax with high mortality in those who are exposed and untreated, clinical guidance that can be quickly implemented must be in place before any intentional release of the agent. This document provides clinical guidance for the prophylaxis and treatment of neonates, infants, children, adolescents, and young adults up to the age of 21 (referred to as "children") in the event of a deliberate B anthracis release and offers guidance in areas where the unique characteristics of children dictate a different clinical recommendation from adults.

Original languageEnglish (US)
Pages (from-to)e1411-e1436
JournalPediatrics
Volume133
Issue number5
DOIs
StatePublished - May 2014

Keywords

  • Anthrax
  • Anthrax vaccine
  • Biological weapon
  • Bioterrorism
  • Children
  • Pediatrics
  • Prophylaxis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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    Bradley, J. S., Krug, S. E., Bower, W. A., Cohn, A. C., Meaney-Delman, D., Pavia, A. T., Chung, S., Fagbuyi, D. B., Fisher, M., Needle, S., Schonfeld, D. J., Alexander, J., Garrett, A., Peacock, G., Phillips, S., Radden, E., Siegel, D., Aird, L., Diederich, S., ... Frantz, J. (2014). Pediatric anthrax clinical management. Pediatrics, 133(5), e1411-e1436. https://doi.org/10.1542/peds.2014-0563