Abstract
Central nervous system tumors are the most common solid malignancy in childhood and the leading cause of cancer-related mortality in children. With an average of 13 new patients being diagnosed daily with a central nervous system tumor, many of these patients will present to the emergency department for evaluation and management. Furthermore, many children experience complications and/or adverse effects directly from the tumor itself, from multimodality treatment (ie, surgery, radiation therapy, and/or chemotherapy), and/or as long-term survivors. Oncologic emergencies include increased intracranial pressure, spinal cord compression, seizures/status epilepticus, central diabetes insipidus, and adrenal insufficiency. Evaluation and management by emergency medicine practitioners are critically important for these patients in all phases of their diagnosis and treatment and can contribute significantly to an improved prognosis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 153-161 |
| Number of pages | 9 |
| Journal | Clinical Pediatric Emergency Medicine |
| Volume | 19 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jun 1 2018 |
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Keywords
- adrenal insufficiency
- central nervous system tumor
- chemotherapy
- diabetes insipidus
- intracranial pressure
- long-term survivor
- radiation therapy
- seizures
- transfusion
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Emergency Medicine
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Pediatric Central Nervous System Tumor Diagnosis, Complications, and Emergencies. / Lenzen, Alicia; Garcia-Sosa, Rebecca; Habiby, Reema L; DiPatri, Arthur J; Pillay Smiley, Natasha.
In: Clinical Pediatric Emergency Medicine, Vol. 19, No. 2, 01.06.2018, p. 153-161.Research output: Contribution to journal › Article
TY - JOUR
T1 - Pediatric Central Nervous System Tumor Diagnosis, Complications, and Emergencies
AU - Lenzen, Alicia
AU - Garcia-Sosa, Rebecca
AU - Habiby, Reema L
AU - DiPatri, Arthur J
AU - Pillay Smiley, Natasha
PY - 2018/6/1
Y1 - 2018/6/1
N2 - Central nervous system tumors are the most common solid malignancy in childhood and the leading cause of cancer-related mortality in children. With an average of 13 new patients being diagnosed daily with a central nervous system tumor, many of these patients will present to the emergency department for evaluation and management. Furthermore, many children experience complications and/or adverse effects directly from the tumor itself, from multimodality treatment (ie, surgery, radiation therapy, and/or chemotherapy), and/or as long-term survivors. Oncologic emergencies include increased intracranial pressure, spinal cord compression, seizures/status epilepticus, central diabetes insipidus, and adrenal insufficiency. Evaluation and management by emergency medicine practitioners are critically important for these patients in all phases of their diagnosis and treatment and can contribute significantly to an improved prognosis.
AB - Central nervous system tumors are the most common solid malignancy in childhood and the leading cause of cancer-related mortality in children. With an average of 13 new patients being diagnosed daily with a central nervous system tumor, many of these patients will present to the emergency department for evaluation and management. Furthermore, many children experience complications and/or adverse effects directly from the tumor itself, from multimodality treatment (ie, surgery, radiation therapy, and/or chemotherapy), and/or as long-term survivors. Oncologic emergencies include increased intracranial pressure, spinal cord compression, seizures/status epilepticus, central diabetes insipidus, and adrenal insufficiency. Evaluation and management by emergency medicine practitioners are critically important for these patients in all phases of their diagnosis and treatment and can contribute significantly to an improved prognosis.
KW - adrenal insufficiency
KW - central nervous system tumor
KW - chemotherapy
KW - diabetes insipidus
KW - intracranial pressure
KW - long-term survivor
KW - radiation therapy
KW - seizures
KW - transfusion
UR - http://www.scopus.com/inward/record.url?scp=85048575761&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85048575761&partnerID=8YFLogxK
U2 - 10.1016/j.cpem.2018.06.003
DO - 10.1016/j.cpem.2018.06.003
M3 - Article
VL - 19
SP - 153
EP - 161
JO - Clinical Pediatric Emergency Medicine
JF - Clinical Pediatric Emergency Medicine
SN - 1522-8401
IS - 2
ER -