Pediatric Erythema Annulare Centrifugum Treated with Oral Fluconazole: A Retrospective Series

Lacey Lea Kruse*, Brandi M Kenner-Bell, Anthony J Mancini

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Objectives: Erythema annulare centrifugum (EAC) is an uncommon eruption that may be a hypersensitivity reaction. Treatment of EAC is best accomplished by eliminating the underlying cause. Although many triggers have been reported, the inciting factor is unknown in most patients. We hypothesized that occult yeast overgrowth may trigger EAC in patients with EAC of unknown etiology. Methods: Five children with EAC were treated empirically with oral fluconazole. These cases were retrospectively reviewed. Results: Improvement was noted in all patients; three cleared entirely. Two patients experienced recurrences after successful treatment, which were treated with a second course of fluconazole. The treatment was well tolerated, without adverse effects. Conclusion: Oral fluconazole was an effective treatment in five children with EAC.

Original languageEnglish (US)
Pages (from-to)501-506
Number of pages6
JournalPediatric Dermatology
Issue number5
StatePublished - Sep 1 2016

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Dermatology


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