Pediatric liver tumors

Marleta Reynolds*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

40 Scopus citations


An infant or child who presents with a large intrahepatic mass will most likely have a malignant tumor. In children, benign tumors constitute only 30% of liver tumors and most are vascular in origin. Treatment of benign vascular tumors is conservative and seldom surgical. Hepatoblastoma is the most common malignant tumor followed by hepatocellular carcinoma. Treatment of malignant tumors is based on a combination of surgery and chemotherapy. Children with hepatic malignancies that can be resected have an excellent prognosis. Other rare benign and malignant tumors of the liver do occur and surgery plays a critical role in management.

Original languageEnglish (US)
Pages (from-to)159-172
Number of pages14
JournalSeminars in Surgical Oncology
Issue number2
StatePublished - Mar 1999


  • Adenomatous polyposis coli
  • Adolescence
  • Adrenal cortex hormones
  • Alpha-fetoproteins
  • Antineoplastic agents
  • Beckwith-Wiedemann syndrome
  • Biopsy
  • Child
  • Cholangiocarcinoma
  • Combined modality therapy
  • Hamartoma
  • Hemangioendothelioma
  • Hemangiosarcoma
  • Hepatoblastoma
  • Hepatocellular carcinoma
  • Incidence
  • Leiomyosarcoma
  • Liver neoplasms
  • Liver transplantation
  • Local neoplasm recurrence
  • Lung neoplasms/secondary
  • Magnetic resonance imaging
  • Mesoderm
  • N ewborn infant
  • Neoplasm metastasis
  • Neoplasm staging
  • Preschool child
  • Prognosis
  • Rhabdomyosarcoma
  • Survival rate
  • Treatment outcome
  • Ultrasound
  • X-ray computed tomography

ASJC Scopus subject areas

  • Surgery
  • Oncology


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