Pediatric psoriasis: Evolving perspectives

Lawrence F. Eichenfield*, Amy S. Paller, Wynnis L. Tom, Jeffrey Sugarman, Adelaide A. Hebert, Sheila Fallon Friedlander, Elaine Siegfried, Nanette Silverberg, Kelly M. Cordoro

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

Background/Objectives: Childhood-onset psoriasis is a common skin disorder that has recently received increasing attention, particularly because of its significant medical, social, financial, and psychological burdens and its associated comorbidities. With limited data available and lack of standardized management guidelines for pediatric psoriasis, an expert panel desired to provide an updated critical overview and practical guidance for management of the affected population. Methods: A panel of pediatric dermatologists with extensive experience in pediatric psoriasis defined and prioritized a core set of topics, performed an English-language literature review, prepared critical evaluations and presentations of topic areas, and carried out a consensus meeting and follow-up consensus manuscript. Results: The summation of evolving perspectives in pediatric psoriasis includes epidemiology and natural history of the disease, precipitating factors and comorbidities, quality of life and burden of disease, clinical features and disease presentation, differential diagnosis, pathogenesis and treatment, including topical, photo, and systemic therapies. Conclusion: Pediatric psoriasis is an important immune-mediated inflammatory skin disease with potential for significant impact on affected individuals and their caregivers. Current state-of-the-art care is based primarily on experience and expert consensus, but pediatric data are accumulating and therapeutic options are rapidly evolving.

Original languageEnglish (US)
Pages (from-to)170-181
Number of pages12
JournalPediatric dermatology
Volume35
Issue number2
DOIs
StatePublished - Mar 1 2018

Keywords

  • clinical
  • disease burden
  • epidemiology
  • pediatrics
  • psoriasis
  • treatment

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Dermatology

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